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Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.
Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. Kramer JS, et al. Among authors: sala a. J Med Chem. 2019 Sep 26;62(18):8443-8460. doi: 10.1021/acs.jmedchem.9b00445. Epub 2019 Sep 17. J Med Chem. 2019. PMID: 31436984 Free PMC article.
Rapid Metabolization of Protectin D1 by β-Oxidation of Its Polar Head Chain.
Balas L, Risé P, Gandrath D, Rovati G, Bolego C, Stellari F, Trenti A, Buccellati C, Durand T, Sala A. Balas L, et al. Among authors: sala a. J Med Chem. 2019 Nov 14;62(21):9961-9975. doi: 10.1021/acs.jmedchem.9b01463. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31626541 Free article.
Transcellular biosynthesis of eicosanoid lipid mediators.
Capra V, Rovati GE, Mangano P, Buccellati C, Murphy RC, Sala A. Capra V, et al. Among authors: sala a. Biochim Biophys Acta. 2015 Apr;1851(4):377-82. doi: 10.1016/j.bbalip.2014.09.002. Epub 2014 Sep 16. Biochim Biophys Acta. 2015. PMID: 25218301 Review.
Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vascular preparations.
Buccellati C, Sala A, Rossoni G, Capra V, Rovati GE, Di Gennaro A, Folco G, Colli S, Casagrande C. Buccellati C, et al. Among authors: sala a. J Pharmacol Exp Ther. 2006 May;317(2):830-7. doi: 10.1124/jpet.105.097170. Epub 2006 Jan 6. J Pharmacol Exp Ther. 2006. PMID: 16399881
1,011 results