Crapser J - Search Results

1

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.

Spangenberg E, Severson PL, Hohsfield LA, Crapser J, Zhang J, Burton EA, Zhang Y, Spevak W, Lin J, Phan NY, Habets G, Rymar A, Tsang G, Walters J, Nespi M, Singh P, Broome S, Ibrahim P, Zhang C, Bollag G, West BL, Green KN. Spangenberg E, et al. Among authors: crapser j. Nat Commun. 2019 Aug 21;10(1):3758. doi: 10.1038/s41467-019-11674-z. Nat Commun. 2019. PMID: 31434879 Free PMC article.

2

Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain.

Crapser JD, Spangenberg EE, Barahona RA, Arreola MA, Hohsfield LA, Green KN. Crapser JD, et al. EBioMedicine. 2020 Aug;58:102919. doi: 10.1016/j.ebiom.2020.102919. Epub 2020 Jul 31. EBioMedicine. 2020. PMID: 32745992 Free PMC article.

3

To Kill a Microglia: A Case for CSF1R Inhibitors.

Green KN, Crapser JD, Hohsfield LA. Green KN, et al. Among authors: crapser jd. Trends Immunol. 2020 Sep;41(9):771-784. doi: 10.1016/j.it.2020.07.001. Epub 2020 Aug 10. Trends Immunol. 2020. PMID: 32792173 Free PMC article. Review.

4

A limited capacity for microglial repopulation in the adult brain.

Najafi AR, Crapser J, Jiang S, Ng W, Mortazavi A, West BL, Green KN. Najafi AR, et al. Among authors: crapser j. Glia. 2018 Nov;66(11):2385-2396. doi: 10.1002/glia.23477. Epub 2018 Oct 28. Glia. 2018. PMID: 30370589 Free PMC article.

5

Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.

Crapser JD, Ochaba J, Soni N, Reidling JC, Thompson LM, Green KN. Crapser JD, et al. Brain. 2020 Jan 1;143(1):266-288. doi: 10.1093/brain/awz363. Brain. 2020. PMID: 31848580 Free PMC article.

6

Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R^+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors.

Arreola MA, Soni N, Crapser JD, Hohsfield LA, Elmore MRP, Matheos DP, Wood MA, Swarup V, Mortazavi A, Green KN. Arreola MA, et al. Among authors: crapser jd. Sci Adv. 2021 Aug 25;7(35):eabg1601. doi: 10.1126/sciadv.abg1601. Print 2021 Aug. Sci Adv. 2021. PMID: 34433559 Free PMC article.

7

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave.

Hohsfield LA, Najafi AR, Ghorbanian Y, Soni N, Crapser J, Figueroa Velez DX, Jiang S, Royer SE, Kim SJ, Henningfield CM, Anderson A, Gandhi SP, Mortazavi A, Inlay MA, Green KN. Hohsfield LA, et al. Among authors: crapser j. Elife. 2021 Aug 23;10:e66738. doi: 10.7554/eLife.66738. Elife. 2021. PMID: 34423781 Free PMC article.

8

Microglia as hackers of the matrix: sculpting synapses and the extracellular space.

Crapser JD, Arreola MA, Tsourmas KI, Green KN. Crapser JD, et al. Cell Mol Immunol. 2021 Nov;18(11):2472-2488. doi: 10.1038/s41423-021-00751-3. Epub 2021 Aug 19. Cell Mol Immunol. 2021. PMID: 34413489 Free PMC article. Review.

9

Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice.

Morozko EL, Ochaba J, Hernandez SJ, Lau A, Sanchez I, Orellana I, Kopan L, Crapser J, Duong JH, Overman J, Yeung S, Steffan JS, Reidling J, Thompson LM. Morozko EL, et al. Among authors: crapser j. J Huntingtons Dis. 2018;7(4):321-335. doi: 10.3233/JHD-180329. J Huntingtons Dis. 2018. PMID: 30452420 Free PMC article.

10

Age- and location-related changes in microglial function.

Ritzel RM, Patel AR, Pan S, Crapser J, Hammond M, Jellison E, McCullough LD. Ritzel RM, et al. Among authors: crapser j. Neurobiol Aging. 2015 Jun;36(6):2153-63. doi: 10.1016/j.neurobiolaging.2015.02.016. Epub 2015 Feb 23. Neurobiol Aging. 2015. PMID: 25816747

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