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Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.
Fabian CJ, Nye L, Powers KR, Nydegger JL, Kreutzjans AL, Phillips TA, Metheny T, Winblad O, Zalles CM, Hagan CR, Goodman ML, Gajewski BJ, Koestler DC, Chalise P, Kimler BF. Fabian CJ, et al. Among authors: hagan cr. Cancer Prev Res (Phila). 2019 Oct;12(10):711-720. doi: 10.1158/1940-6207.CAPR-19-0315. Epub 2019 Aug 16. Cancer Prev Res (Phila). 2019. PMID: 31420361 Free PMC article. Clinical Trial.
NEMO, a Transcriptional Target of Estrogen and Progesterone, Is Linked to Tumor Suppressor PML in Breast Cancer.
Elsarraj HS, Valdez KE, Hong Y, Grimm SL, Ricci LR, Fan F, Tawfik O, May L, Cusick T, Inciardi M, Redick M, Gatewood J, Winblad O, Hilsenbeck S, Edwards DP, Hagan CR, Godwin AK, Fabian C, Behbod F. Elsarraj HS, et al. Among authors: hagan cr. Cancer Res. 2017 Jul 15;77(14):3802-3813. doi: 10.1158/0008-5472.CAN-16-2794. Epub 2017 May 17. Cancer Res. 2017. PMID: 28515148 Free PMC article.
Interferon-Stimulated Genes Are Transcriptionally Repressed by PR in Breast Cancer.
Walter KR, Goodman ML, Singhal H, Hall JA, Li T, Holloran SM, Trinca GM, Gibson KA, Jin VX, Greene GL, Hagan CR. Walter KR, et al. Among authors: hagan cr. Mol Cancer Res. 2017 Oct;15(10):1331-1340. doi: 10.1158/1541-7786.MCR-17-0180. Epub 2017 Jul 6. Mol Cancer Res. 2017. PMID: 28684637 Free PMC article.
Progesterone Receptor Attenuates STAT1-Mediated IFN Signaling in Breast Cancer.
Goodman ML, Trinca GM, Walter KR, Papachristou EK, D'Santos CS, Li T, Liu Q, Lai Z, Chalise P, Madan R, Fan F, Markiewicz MA, Jin VX, Carroll JS, Hagan CR. Goodman ML, et al. Among authors: hagan cr. J Immunol. 2019 May 15;202(10):3076-3086. doi: 10.4049/jimmunol.1801152. Epub 2019 Apr 1. J Immunol. 2019. PMID: 30936295 Free PMC article.
Progesterone promotes immunomodulation and tumor development in the murine mammary gland.
Werner LR, Gibson KA, Goodman ML, Helm DE, Walter KR, Holloran SM, Trinca GM, Hastings RC, Yang HH, Hu Y, Wei J, Lei G, Yang XY, Madan R, Molinolo AA, Markiewicz MA, Chalise P, Axelrod ML, Balko JM, Hunter KW, Hartman ZC, Lange CA, Hagan CR. Werner LR, et al. Among authors: hagan cr. J Immunother Cancer. 2021 May;9(5):e001710. doi: 10.1136/jitc-2020-001710. J Immunother Cancer. 2021. PMID: 33958486 Free PMC article.
Site-specific O-GlcNAcylation of progesterone receptor (PR) supports PR attenuation of interferon stimulated genes (ISGs) and tumor growth in breast cancer.
Saunders HI, Holloran SM, Trinca GM, Artigues A, Villar M, Tinoco JC, Dias WB, Werner LR, Chowanec EI, Heard A, Chalise P, Slawson C, Hagan CR. Saunders HI, et al. Among authors: hagan cr. J Biol Chem. 2024 Oct 11;300(11):107886. doi: 10.1016/j.jbc.2024.107886. Online ahead of print. J Biol Chem. 2024. PMID: 39395796 Free article.
62 results