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AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart.
Pan X, Yue Y, Zhang K, Hakim CH, Kodippili K, McDonald T, Duan D. Pan X, et al. Among authors: kodippili k. Hum Gene Ther Methods. 2015 Apr;26(2):54-61. doi: 10.1089/hgtb.2014.128. Epub 2015 Apr 1. Hum Gene Ther Methods. 2015. PMID: 25763686 Free PMC article.
Dystrophin contains multiple independent membrane-binding domains.
Zhao J, Kodippili K, Yue Y, Hakim CH, Wasala L, Pan X, Zhang K, Yang NN, Duan D, Lai Y. Zhao J, et al. Among authors: kodippili k. Hum Mol Genet. 2016 Sep 1;25(17):3647-3653. doi: 10.1093/hmg/ddw210. Epub 2016 Jul 4. Hum Mol Genet. 2016. PMID: 27378693 Free PMC article.
A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy.
Hakim CH, Wasala NB, Pan X, Kodippili K, Yue Y, Zhang K, Yao G, Haffner B, Duan SX, Ramos J, Schneider JS, Yang NN, Chamberlain JS, Duan D. Hakim CH, et al. Among authors: kodippili k. Mol Ther Methods Clin Dev. 2017 Jul 27;6:216-230. doi: 10.1016/j.omtm.2017.06.006. eCollection 2017 Sep 15. Mol Ther Methods Clin Dev. 2017. PMID: 28932757 Free PMC article.
AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice.
Hakim CH, Wasala NB, Nelson CE, Wasala LP, Yue Y, Louderman JA, Lessa TB, Dai A, Zhang K, Jenkins GJ, Nance ME, Pan X, Kodippili K, Yang NN, Chen SJ, Gersbach CA, Duan D. Hakim CH, et al. Among authors: kodippili k. JCI Insight. 2018 Dec 6;3(23):e124297. doi: 10.1172/jci.insight.124297. JCI Insight. 2018. PMID: 30518686 Free PMC article.
16 results