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Systemic AAV vectors for widespread and targeted gene delivery in rodents.
Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Challis RC, et al. Nat Protoc. 2019 Feb;14(2):379-414. doi: 10.1038/s41596-018-0097-3. Nat Protoc. 2019. PMID: 30626963
Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies.
Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K. Rajendran PS, et al. Among authors: challis rc. Nat Commun. 2019 Apr 26;10(1):1944. doi: 10.1038/s41467-019-09770-1. Nat Commun. 2019. PMID: 31028266 Free PMC article.
Adeno-Associated Virus Toolkit to Target Diverse Brain Cells.
Challis RC, Ravindra Kumar S, Chen X, Goertsen D, Coughlin GM, Hori AM, Chuapoco MR, Otis TS, Miles TF, Gradinaru V. Challis RC, et al. Annu Rev Neurosci. 2022 Jul 8;45:447-469. doi: 10.1146/annurev-neuro-111020-100834. Epub 2022 Apr 19. Annu Rev Neurosci. 2022. PMID: 35440143 Free article. Review.
Glutamate in primary afferents is required for itch transmission.
Cui L, Guo J, Cranfill SL, Gautam M, Bhattarai J, Olson W, Beattie K, Challis RC, Wu Q, Song X, Raabe T, Gradinaru V, Ma M, Liu Q, Luo W. Cui L, et al. Among authors: challis rc. Neuron. 2022 Mar 2;110(5):809-823.e5. doi: 10.1016/j.neuron.2021.12.007. Epub 2022 Jan 4. Neuron. 2022. PMID: 34986325 Free PMC article.
Sour taste finds closure in a potassium channel.
Challis RC, Ma M. Challis RC, et al. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):246-7. doi: 10.1073/pnas.1523319113. Epub 2015 Dec 30. Proc Natl Acad Sci U S A. 2016. PMID: 26719421 Free PMC article. No abstract available.
17 results