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Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole TM, Toedling J, Sprüssel A, Pfeil S, Savelyeva L, Capper D, Messerschmidt C, Beule D, Groeneveld-Krentz S, Eckert C, Gambara G, Henssen AG, Finkler S, Schulte JH, Sieber A, Bluethgen N, Regenbrecht CRA, Künkele A, Lodrini M, Eggert A, Deubzer HE. Thole TM, et al. Among authors: lodrini m. Int J Cancer. 2020 Feb 15;146(4):1031-1041. doi: 10.1002/ijc.32572. Epub 2019 Aug 1. Int J Cancer. 2020. PMID: 31304977
Targeting histone deacetylases in neuroblastoma.
Witt O, Deubzer HE, Lodrini M, Milde T, Oehme I. Witt O, et al. Among authors: lodrini m. Curr Pharm Des. 2009;15(4):436-47. doi: 10.2174/138161209787315774. Curr Pharm Des. 2009. PMID: 19199971 Review.
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Milde T, Kleber S, Korshunov A, Witt H, Hielscher T, Koch P, Kopp HG, Jugold M, Deubzer HE, Oehme I, Lodrini M, Gröne HJ, Benner A, Brüstle O, Gilbertson RJ, von Deimling A, Kulozik AE, Pfister SM, Martin-Villalba A, Witt O. Milde T, et al. Among authors: lodrini m. Acta Neuropathol. 2011 Nov;122(5):637-50. doi: 10.1007/s00401-011-0866-3. Epub 2011 Aug 24. Acta Neuropathol. 2011. PMID: 21863243 Free PMC article.
Nestin expression identifies ependymoma patients with poor outcome.
Milde T, Hielscher T, Witt H, Kool M, Mack SC, Deubzer HE, Oehme I, Lodrini M, Benner A, Taylor MD, von Deimling A, Kulozik AE, Pfister SM, Witt O, Korshunov A. Milde T, et al. Among authors: lodrini m. Brain Pathol. 2012 Nov;22(6):848-60. doi: 10.1111/j.1750-3639.2012.00600.x. Epub 2012 May 30. Brain Pathol. 2012. PMID: 22568867 Free PMC article.
HDAC11 is a novel drug target in carcinomas.
Deubzer HE, Schier MC, Oehme I, Lodrini M, Haendler B, Sommer A, Witt O. Deubzer HE, et al. Among authors: lodrini m. Int J Cancer. 2013 May 1;132(9):2200-8. doi: 10.1002/ijc.27876. Epub 2012 Oct 25. Int J Cancer. 2013. PMID: 23024001
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
Lodrini M, Oehme I, Schroeder C, Milde T, Schier MC, Kopp-Schneider A, Schulte JH, Fischer M, De Preter K, Pattyn F, Castoldi M, Muckenthaler MU, Kulozik AE, Westermann F, Witt O, Deubzer HE. Lodrini M, et al. Nucleic Acids Res. 2013 Jul;41(12):6018-33. doi: 10.1093/nar/gkt346. Epub 2013 Apr 26. Nucleic Acids Res. 2013. PMID: 23625969 Free PMC article.
Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme I, Linke JP, Böck BC, Milde T, Lodrini M, Hartenstein B, Wiegand I, Eckert C, Roth W, Kool M, Kaden S, Gröne HJ, Schulte JH, Lindner S, Hamacher-Brady A, Brady NR, Deubzer HE, Witt O. Oehme I, et al. Among authors: lodrini m. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2592-601. doi: 10.1073/pnas.1300113110. Epub 2013 Jun 25. Proc Natl Acad Sci U S A. 2013. PMID: 23801752 Free PMC article.
29 results