The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
Marx CE, Trost WT, Shampine LJ, Stevens RD, Hulette CM, Steffens DC, Ervin JF, Butterfield MI, Blazer DG, Massing MW, Lieberman JA.
Marx CE, et al.
Biol Psychiatry. 2006 Dec 15;60(12):1287-94. doi: 10.1016/j.biopsych.2006.06.017. Epub 2006 Sep 25.
Biol Psychiatry. 2006.
PMID: 16997284