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Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).
Maiwald CA, Annink KV, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Guimarães H, Stiris T, Cattarossi L, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, Jacobs Y, Franz AR; ALBINO Study Group. Maiwald CA, et al. Among authors: annink kv. BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8. BMC Pediatr. 2019. PMID: 31248390 Free PMC article.
Allopurinol: Old Drug, New Indication in Neonates?
Annink KV, Franz AR, Derks JB, Rudiger M, Bel FV, Benders MJNL. Annink KV, et al. Curr Pharm Des. 2017;23(38):5935-5942. doi: 10.2174/1381612823666170918123307. Curr Pharm Des. 2017. PMID: 28925896 Review.
The long-term effect of perinatal asphyxia on hippocampal volumes.
Annink KV, de Vries LS, Groenendaal F, van den Heuvel MP, van Haren NEM, Swaab H, van Handel M, Jongmans MJ, Benders MJ, van der Aa NE. Annink KV, et al. Pediatr Res. 2019 Jan;85(1):43-49. doi: 10.1038/s41390-018-0115-8. Epub 2018 Jul 17. Pediatr Res. 2019. PMID: 30254237
Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance.
Deferm N, Annink KV, Faelens R, Schroth M, Maiwald CA, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Smits A, Annaert P, Franz AR, Allegaert K; ALBINO Study Group. Deferm N, et al. Among authors: annink kv. Clin Pharmacokinet. 2021 Jul;60(7):897-906. doi: 10.1007/s40262-021-00991-6. Epub 2021 Feb 21. Clin Pharmacokinet. 2021. PMID: 33611729 Free PMC article. Clinical Trial.
Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.
Chu WY, Annink KV, Nijstad AL, Maiwald CA, Schroth M, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Franz AR, Dorlo TPC, Allegaert K, Huitema ADR; ALBINO Study Group. Chu WY, et al. Among authors: annink kv. Clin Pharmacokinet. 2022 Feb;61(2):321-333. doi: 10.1007/s40262-021-01068-0. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617261 Free PMC article. Clinical Trial.
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