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Page 1
Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice.
Zhu Y, Blum M, Hoff U, Wesser T, Fechner M, Westphal C, Gürgen D, Catar RA, Philippe A, Wu K, Bubalo G, Rothe M, Weldon SM, Dragun D, Schunck WH. Zhu Y, et al. Among authors: schunck wh. PLoS One. 2016 Jan 4;11(1):e0145645. doi: 10.1371/journal.pone.0145645. eCollection 2016. PLoS One. 2016. PMID: 26727266 Free PMC article.
Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.
Hoff U, Lukitsch I, Chaykovska L, Ladwig M, Arnold C, Manthati VL, Fuller TF, Schneider W, Gollasch M, Muller DN, Flemming B, Seeliger E, Luft FC, Falck JR, Dragun D, Schunck WH. Hoff U, et al. Among authors: schunck wh. Kidney Int. 2011 Jan;79(1):57-65. doi: 10.1038/ki.2010.377. Epub 2010 Oct 20. Kidney Int. 2011. PMID: 20962739 Free PMC article.
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gösele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC, Hubner N. Monti J, et al. Among authors: schunck wh. Nat Genet. 2008 May;40(5):529-37. doi: 10.1038/ng.129. Nat Genet. 2008. PMID: 18443590 Free PMC article.
Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
Boldt C, Röschel T, Himmerkus N, Plain A, Bleich M, Labes R, Blum M, Krause H, Magheli A, Giesecke T, Mutig K, Rothe M, Weldon SM, Dragun D, Schunck WH, Bachmann S, Paliege A. Boldt C, et al. Among authors: schunck wh. Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1198-F1210. doi: 10.1152/ajprenal.00062.2016. Epub 2016 Sep 28. Am J Physiol Renal Physiol. 2016. PMID: 27681558 Free article.
Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. Hasegawa E, et al. Among authors: schunck wh. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7545-E7553. doi: 10.1073/pnas.1620898114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827330 Free PMC article.
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff U, Bubalo G, Fechner M, Blum M, Zhu Y, Pohlmann A, Hentschel J, Arakelyan K, Seeliger E, Flemming B, Gürgen D, Rothe M, Niendorf T, Manthati VL, Falck JR, Haase M, Schunck WH, Dragun D. Hoff U, et al. Among authors: schunck wh. Acta Physiol (Oxf). 2019 Oct;227(2):e13297. doi: 10.1111/apha.13297. Epub 2019 Jun 2. Acta Physiol (Oxf). 2019. PMID: 31077555 Free PMC article.
124 results