Wei W - Search Results

1

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. Zhang J, et al. Among authors: wei w. Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19. Cancer Discov. 2019. PMID: 31217297 Free PMC article.

2

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, Kaelin WG Jr, Harper JW, Wei W. Inuzuka H, et al. Among authors: wei w. Cancer Cell. 2010 Aug 9;18(2):147-59. doi: 10.1016/j.ccr.2010.06.015. Cancer Cell. 2010. PMID: 20708156 Free PMC article.

3

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. Gao D, et al. Among authors: wei w. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. Mol Cell. 2011. PMID: 22017875 Free PMC article.

4

miR-23a, a critical regulator of "migR"ation and metastasis in colorectal cancer.

Wang Z, Wei W, Sarkar FH. Wang Z, et al. Among authors: wei w. Cancer Discov. 2012 Jun;2(6):489-91. doi: 10.1158/2159-8290.CD-12-0177. Cancer Discov. 2012. PMID: 22684455 Free PMC article.

5

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. Fukushima H, et al. Among authors: wei w. Cell Rep. 2012 May 31;1(5):434-43. doi: 10.1016/j.celrep.2012.04.002. Cell Rep. 2012. PMID: 22708077 Free PMC article.

6

Acetylation-dependent regulation of Skp2 function.

Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, Haigis MC, Pandolfi PP, Wei W. Inuzuka H, et al. Among authors: wei w. Cell. 2012 Jul 6;150(1):179-93. doi: 10.1016/j.cell.2012.05.038. Cell. 2012. PMID: 22770219 Free PMC article.

7

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

Chen H, Ma H, Inuzuka H, Diao J, Lan F, Shi YG, Wei W, Shi Y. Chen H, et al. Among authors: wei w. Mol Cell Biol. 2013 Mar;33(6):1139-48. doi: 10.1128/MCB.01191-12. Epub 2013 Jan 7. Mol Cell Biol. 2013. PMID: 23297342 Free PMC article.

8

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: wei w. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.

9

Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity.

Liu P, Guo J, Gan W, Wei W. Liu P, et al. Among authors: wei w. Protein Cell. 2014 Mar;5(3):171-7. doi: 10.1007/s13238-014-0021-8. Protein Cell. 2014. PMID: 24481632 Free PMC article.

10

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Among authors: wei w. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

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