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Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure determination, table of crystallographic data, table of crystallographic parameters and refinement statistics, figures showing binding mode and distances, procedures for mass spectrometry measurements, differential scanning fluorimetry measurements, stopped-flow measurements and other kinetics measurements. See DOI: 10.1039/c4sc01752hClick here for additional data file.
Brem J, Struwe WB, Rydzik AM, Tarhonskaya H, Pfeffer I, Flashman E, van Berkel SS, Spencer J, Claridge TD, McDonough MA, Benesch JL, Schofield CJ. Brem J, et al. Among authors: struwe wb. Chem Sci. 2015 Feb 19;6(2):956-963. doi: 10.1039/c4sc01752h. Epub 2014 Nov 4. Chem Sci. 2015. PMID: 25717359 Free PMC article.
Optimal Synthetic Glycosylation of a Therapeutic Antibody.
Parsons TB, Struwe WB, Gault J, Yamamoto K, Taylor TA, Raj R, Wals K, Mohammed S, Robinson CV, Benesch JL, Davis BG. Parsons TB, et al. Among authors: struwe wb. Angew Chem Int Ed Engl. 2016 Feb 12;55(7):2361-7. doi: 10.1002/anie.201508723. Epub 2016 Jan 12. Angew Chem Int Ed Engl. 2016. PMID: 26756880 Free PMC article.
High-resolution mass spectrometry of small molecules bound to membrane proteins.
Gault J, Donlan JA, Liko I, Hopper JT, Gupta K, Housden NG, Struwe WB, Marty MT, Mize T, Bechara C, Zhu Y, Wu B, Kleanthous C, Belov M, Damoc E, Makarov A, Robinson CV. Gault J, et al. Among authors: struwe wb. Nat Methods. 2016 Apr;13(4):333-6. doi: 10.1038/nmeth.3771. Epub 2016 Feb 22. Nat Methods. 2016. PMID: 26901650 Free PMC article.
Optimal Synthetic Glycosylation of a Therapeutic Antibody.
Parsons TB, Struwe WB, Gault J, Yamamoto K, Taylor TA, Raj R, Wals K, Mohammed S, Robinson CV, Benesch JL, Davis BG. Parsons TB, et al. Among authors: struwe wb. Angew Chem Weinheim Bergstr Ger. 2016 Feb 12;128(7):2407-2413. doi: 10.1002/ange.201508723. Epub 2016 Jan 12. Angew Chem Weinheim Bergstr Ger. 2016. PMID: 27546920 Free PMC article.
The role of interfacial lipids in stabilizing membrane protein oligomers.
Gupta K, Donlan JAC, Hopper JTS, Uzdavinys P, Landreh M, Struwe WB, Drew D, Baldwin AJ, Stansfeld PJ, Robinson CV. Gupta K, et al. Among authors: struwe wb. Nature. 2017 Jan 19;541(7637):421-424. doi: 10.1038/nature20820. Epub 2017 Jan 11. Nature. 2017. PMID: 28077870 Free PMC article.
The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.
Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB, Crispin M, Doores KJ, Woods RJ, Benesch JLP, Robinson CV, Struwe WB. Hopper JTS, et al. Among authors: struwe wb. Structure. 2017 May 2;25(5):773-782.e5. doi: 10.1016/j.str.2017.03.015. Epub 2017 Apr 20. Structure. 2017. PMID: 28434916 Free PMC article.
N-glycan microheterogeneity regulates interactions of plasma proteins.
Wu D, Struwe WB, Harvey DJ, Ferguson MAJ, Robinson CV. Wu D, et al. Among authors: struwe wb. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):8763-8768. doi: 10.1073/pnas.1807439115. Epub 2018 Aug 15. Proc Natl Acad Sci U S A. 2018. PMID: 30111543 Free PMC article.
In-depth structural analysis of glycans in the gas phase.
Mucha E, Stuckmann A, Marianski M, Struwe WB, Meijer G, Pagel K. Mucha E, et al. Among authors: struwe wb. Chem Sci. 2019 Jan 4;10(5):1272-1284. doi: 10.1039/c8sc05426f. eCollection 2019 Feb 7. Chem Sci. 2019. PMID: 30809341 Free PMC article. Review.
107 results