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A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2.
Li Y, Song Y, Zhao M, Guo Y, Yu C, Chen W, Shao S, Xu C, Zhou X, Zhao L, Zhang Z, Bo T, Xia Y, Proud CG, Wang X, Wang L, Zhao J, Gao L. Li Y, et al. Hepatology. 2017 Aug;66(2):481-497. doi: 10.1002/hep.29206. Epub 2017 Jun 27. Hepatology. 2017. PMID: 28395113 Free PMC article.
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol.
Guo Y, Zhao M, Bo T, Ma S, Yuan Z, Chen W, He Z, Hou X, Liu J, Zhang Z, Zhu Q, Wang Q, Lin X, Yang Z, Cui M, Liu L, Li Y, Yu C, Qi X, Wang Q, Zhang H, Guan Q, Zhao L, Xuan S, Yan H, Lin Y, Wang L, Li Q, Song Y, Gao L, Zhao J. Guo Y, et al. Among authors: li y, li q. Cell Res. 2019 Feb;29(2):151-166. doi: 10.1038/s41422-018-0123-6. Epub 2018 Dec 17. Cell Res. 2019. PMID: 30559440 Free PMC article.
Hepatic ERK activity plays a role in energy metabolism.
Jiao P, Feng B, Li Y, He Q, Xu H. Jiao P, et al. Among authors: li y. Mol Cell Endocrinol. 2013 Aug 15;375(1-2):157-66. doi: 10.1016/j.mce.2013.05.021. Epub 2013 May 31. Mol Cell Endocrinol. 2013. PMID: 23732116 Free PMC article.
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