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A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.
Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, Snyder NW, Gupta RK, Seale P. Wang W, et al. Among authors: rabinowitz jd. Cell Metab. 2019 Jul 2;30(1):174-189.e5. doi: 10.1016/j.cmet.2019.05.005. Epub 2019 May 30. Cell Metab. 2019. PMID: 31155495 Free PMC article.
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. Jang C, et al. Among authors: rabinowitz jd. Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7. Nat Med. 2016. PMID: 26950361 Free PMC article.
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.
Frederick DW, Loro E, Liu L, Davila A Jr, Chellappa K, Silverman IM, Quinn WJ 3rd, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, Nakamaru-Ogiso E, Rabinowitz JD, Khurana TS, Baur JA. Frederick DW, et al. Among authors: rabinowitz jd. Cell Metab. 2016 Aug 9;24(2):269-82. doi: 10.1016/j.cmet.2016.07.005. Cell Metab. 2016. PMID: 27508874 Free PMC article.
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.
Liu L, Su X, Quinn WJ 3rd, Hui S, Krukenberg K, Frederick DW, Redpath P, Zhan L, Chellappa K, White E, Migaud M, Mitchison TJ, Baur JA, Rabinowitz JD. Liu L, et al. Among authors: rabinowitz jd. Cell Metab. 2018 May 1;27(5):1067-1080.e5. doi: 10.1016/j.cmet.2018.03.018. Cell Metab. 2018. PMID: 29685734 Free PMC article.
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids.
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. Neinast MD, et al. Among authors: rabinowitz jd. Cell Metab. 2019 Feb 5;29(2):417-429.e4. doi: 10.1016/j.cmet.2018.10.013. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449684 Free PMC article.
307 results