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Live-Animal Epigenome Editing: Convergence of Novel Techniques.
Gomez JA, Beitnere U, Segal DJ. Gomez JA, et al. Among authors: segal dj. Trends Genet. 2019 Jul;35(7):527-541. doi: 10.1016/j.tig.2019.04.007. Epub 2019 May 22. Trends Genet. 2019. PMID: 31128888 Free PMC article. Review.
How specific is CRISPR/Cas9 really?
O'Geen H, Yu AS, Segal DJ. O'Geen H, et al. Among authors: segal dj. Curr Opin Chem Biol. 2015 Dec;29:72-8. doi: 10.1016/j.cbpa.2015.10.001. Epub 2015 Oct 24. Curr Opin Chem Biol. 2015. PMID: 26517564 Free PMC article. Review.
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.
Berg EL, Pride MC, Petkova SP, Lee RD, Copping NA, Shen Y, Adhikari A, Fenton TA, Pedersen LR, Noakes LS, Nieman BJ, Lerch JP, Harris S, Born HA, Peters MM, Deng P, Cameron DL, Fink KD, Beitnere U, O'Geen H, Anderson AE, Dindot SV, Nash KR, Weeber EJ, Wöhr M, Ellegood J, Segal DJ, Silverman JL. Berg EL, et al. Among authors: segal dj. Transl Psychiatry. 2020 Jan 27;10(1):39. doi: 10.1038/s41398-020-0720-2. Transl Psychiatry. 2020. PMID: 32066685 Free PMC article.
An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models.
Deng P, Halmai JANM, Beitnere U, Cameron D, Martinez ML, Lee CC, Waldo JJ, Thongphanh K, Adhikari A, Copping N, Petkova SP, Lee RD, Lock S, Palomares M, O'Geen H, Carter J, Gonzalez CE, Buchanan FKB, Anderson JD, Fierro FA, Nolta JA, Tarantal AF, Silverman JL, Segal DJ, Fink KD. Deng P, et al. Among authors: segal dj. Front Mol Neurosci. 2022 Jan 27;14:789913. doi: 10.3389/fnmol.2021.789913. eCollection 2021. Front Mol Neurosci. 2022. PMID: 35153670 Free PMC article.
Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons.
Fugon OJG, Sharifi O, Heath NG, Soto DC, Gomez JA, Yasui DH, Mendiola AJP, O'Geen H, Beitnere U, Tomkova M, Haghani V, Dillon G, Segal DJ, LaSalle J. Fugon OJG, et al. Among authors: segal dj. bioRxiv [Preprint]. 2024 Mar 29:2024.03.26.586689. doi: 10.1101/2024.03.26.586689. bioRxiv. 2024. Update in: Hum Mol Genet. 2024 Sep 19;33(19):1711-1725. doi: 10.1093/hmg/ddae111. PMID: 38586056 Free PMC article. Updated. Preprint.
Genome engineering at the dawn of the golden age.
Segal DJ, Meckler JF. Segal DJ, et al. Annu Rev Genomics Hum Genet. 2013;14:135-58. doi: 10.1146/annurev-genom-091212-153435. Epub 2013 May 20. Annu Rev Genomics Hum Genet. 2013. PMID: 23701416 Review.
120 results