Fang C - Search Results

1

ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.

Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Fang C, et al. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. Nat Commun. 2019. PMID: 31113953 Free PMC article.

2

Innate immune mechanisms in transplant allograft vasculopathy.

Jane-Wit D, Fang C, Goldstein DR. Jane-Wit D, et al. Among authors: fang c. Curr Opin Organ Transplant. 2016 Jun;21(3):253-7. doi: 10.1097/MOT.0000000000000314. Curr Opin Organ Transplant. 2016. PMID: 27077602 Free PMC article. Review.

3

Complement C5 Inhibition Reduces T Cell-Mediated Allograft Vasculopathy Caused by Both Alloantibody and Ischemia Reperfusion Injury in Humanized Mice.

Qin L, Li G, Kirkiles-Smith N, Clark P, Fang C, Wang Y, Yu ZX, Devore D, Tellides G, Pober JS, Jane-Wit D. Qin L, et al. Among authors: fang c. Am J Transplant. 2016 Oct;16(10):2865-2876. doi: 10.1111/ajt.13834. Epub 2016 Jun 14. Am J Transplant. 2016. PMID: 27104811 Free PMC article.

4

IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium.

Liu R, Lauridsen HM, Amezquita RA, Pierce RW, Jane-Wit D, Fang C, Pellowe AS, Kirkiles-Smith NC, Gonzalez AL, Pober JS. Liu R, et al. Among authors: fang c. J Immunol. 2016 Sep 15;197(6):2400-8. doi: 10.4049/jimmunol.1600138. Epub 2016 Aug 17. J Immunol. 2016. PMID: 27534549 Free PMC article.

5

Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1.

Liu R, Merola J, Manes TD, Qin L, Tietjen GT, López-Giráldez F, Broecker V, Fang C, Xie C, Chen PM, Kirkiles-Smith NC, Jane-Wit D, Pober JS. Liu R, et al. Among authors: fang c. JCI Insight. 2018 Mar 8;3(5):e97881. doi: 10.1172/jci.insight.97881. JCI Insight. 2018. PMID: 29515027 Free PMC article.

6

Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-γ-Primed Human Endothelium.

Xie CB, Qin L, Li G, Fang C, Kirkiles-Smith NC, Tellides G, Pober JS, Jane-Wit D. Xie CB, et al. Among authors: fang c. Circ Res. 2019 Jun 7;124(12):1747-1759. doi: 10.1161/CIRCRESAHA.119.314845. Epub 2019 Apr 22. Circ Res. 2019. PMID: 31170059 Free PMC article.

7

Endothelial Cell-Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production.

Liu L, Fang C, Fu W, Jiang B, Li G, Qin L, Rosenbluth J, Gong G, Xie CB, Yoo P, Tellides G, Pober JS, Jane-Wit D. Liu L, et al. Among authors: fang c. Circulation. 2020 Feb 11;141(6):464-478. doi: 10.1161/CIRCULATIONAHA.119.042501. Epub 2019 Nov 20. Circulation. 2020. PMID: 31744330 Free PMC article.

8

Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells.

Jiang B, Wang S, Song G, Jiang Q, Fan M, Fang C, Li X, Soh CL, Manes TD, Cheru N, Qin L, Ren P, Jortner B, Wang Q, Quaranta E, Yoo P, Geirsson A, Davis RP, Tellides G, Pober JS, Jane-Wit D. Jiang B, et al. Among authors: fang c. Sci Signal. 2023 Mar 21;16(777):eabo3406. doi: 10.1126/scisignal.abo3406. Epub 2023 Mar 21. Sci Signal. 2023. PMID: 36943921 Free PMC article.

9

A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells.

Li X, Jiang Q, Song G, Barkestani MN, Wang Q, Wang S, Fan M, Fang C, Jiang B, Johnson J, Geirsson A, Tellides G, Pober JS, Jane-Wit D. Li X, et al. Among authors: fang c. Nat Commun. 2023 May 24;14(1):3002. doi: 10.1038/s41467-023-38684-2. Nat Commun. 2023. PMID: 37225719 Free PMC article.

10

Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells.

Li X, Jiang Q, Song G, Barkestani MN, Wang Q, Wang S, Fan M, Fang C, Jiang B, Johnson J, Geirsson A, Tellides G, Pober JS, Jane-Wit D. Li X, et al. Among authors: fang c. Nat Commun. 2023 Jun 7;14(1):3336. doi: 10.1038/s41467-023-39154-5. Nat Commun. 2023. PMID: 37286577 Free PMC article. No abstract available.

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