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Tumor-associated antigen expressing Listeria monocytogenes induces effective primary and memory T-cell responses against hepatic colorectal cancer metastases.
Olino K, Wada S, Edil BH, Pan X, Meckel K, Weber W, Slansky J, Tamada K, Lauer P, Brockstedt D, Pardoll D, Schulick R, Yoshimura K. Olino K, et al. Among authors: lauer p. Ann Surg Oncol. 2012 Jul;19 Suppl 3(Suppl 3):S597-607. doi: 10.1245/s10434-011-2037-0. Epub 2011 Oct 7. Ann Surg Oncol. 2012. PMID: 21979110 Free PMC article.
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Keenan BP, Saenger Y, Kafrouni MI, Leubner A, Lauer P, Maitra A, Rucki AA, Gunderson AJ, Coussens LM, Brockstedt DG, Dubensky TW Jr, Hassan R, Armstrong TD, Jaffee EM. Keenan BP, et al. Among authors: lauer p. Gastroenterology. 2014 Jun;146(7):1784-94.e6. doi: 10.1053/j.gastro.2014.02.055. Epub 2014 Mar 6. Gastroenterology. 2014. PMID: 24607504 Free PMC article.
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.
Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, Woodward JJ, Pardoll DM, Dubensky TW Jr, Kim Y. Fu J, et al. Among authors: lauer p. Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306. Sci Transl Med. 2015. PMID: 25877890 Free PMC article.
Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate cancer.
Drake CG, Pachynski RK, Subudhi SK, McNeel DG, Antonarakis ES, Bauer TM, Lauer P, Brockstedt D, Patricia D, Wade M, Zudaire E, Bandyopadhyay N, Parasrampuria DA, Girgis S, Mason GE, Knoblauch RE, Stone N, Infante JR, Gottardis MM, Fong L. Drake CG, et al. Among authors: lauer p. Prostate Cancer Prostatic Dis. 2022 Feb;25(2):219-228. doi: 10.1038/s41391-021-00402-8. Epub 2021 Jul 13. Prostate Cancer Prostatic Dis. 2022. PMID: 34257408 Free PMC article.
Heterologous vaccination targeting prostatic acid phosphatase (PAP) using DNA and Listeria vaccines elicits superior anti-tumor immunity dependent on CD4+ T cells elicited by DNA priming.
Johnson LE, Brockstedt D, Leong M, Lauer P, Theisen E, Sauer JD, McNeel DG. Johnson LE, et al. Among authors: lauer p. Oncoimmunology. 2018 May 7;7(8):e1456603. doi: 10.1080/2162402X.2018.1456603. eCollection 2018. Oncoimmunology. 2018. PMID: 30221049 Free PMC article.
A Potent and Effective Suicidal Listeria Vaccine Platform.
Hanson WG, Benanti EL, Lemmens EE, Liu W, Skoble J, Leong ML, Rae CS, Fassò M, Brockstedt DG, Chen C, Portnoy DA, Dubensky TW Jr, Lauer P. Hanson WG, et al. Among authors: lauer p. Infect Immun. 2019 Jul 23;87(8):e00144-19. doi: 10.1128/IAI.00144-19. Print 2019 Aug. Infect Immun. 2019. PMID: 31235641 Free PMC article.
Killed but metabolically active vaccines.
Dubensky TW Jr, Skoble J, Lauer P, Brockstedt DG. Dubensky TW Jr, et al. Among authors: lauer p. Curr Opin Biotechnol. 2012 Dec;23(6):917-23. doi: 10.1016/j.copbio.2012.04.005. Epub 2012 May 18. Curr Opin Biotechnol. 2012. PMID: 22608846 Review.
Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination.
Jackson CM, Kochel CM, Nirschl CJ, Durham NM, Ruzevick J, Alme A, Francica BJ, Elias J, Daniels A, Dubensky TW Jr, Lauer P, Brockstedt DG, Baxi EG, Calabresi PA, Taube JM, Pardo CA, Brem H, Pardoll DM, Lim M, Drake CG. Jackson CM, et al. Among authors: lauer p. Clin Cancer Res. 2016 Mar 1;22(5):1161-72. doi: 10.1158/1078-0432.CCR-15-1516. Epub 2015 Oct 21. Clin Cancer Res. 2016. PMID: 26490306 Free PMC article.
62 results