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Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for maturation.
Poon E, Yan B, Zhang S, Rushing S, Keung W, Ren L, Lieu DK, Geng L, Kong CW, Wang J, Wong HS, Boheler KR, Li RA. Poon E, et al. Among authors: ren l. PLoS One. 2013 Oct 21;8(10):e77784. doi: 10.1371/journal.pone.0077784. eCollection 2013. PLoS One. 2013. PMID: 24204964 Free PMC article.
A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells.
Weng Z, Kong CW, Ren L, Karakikes I, Geng L, He J, Chow MZ, Mok CF, Chan HYS, Webb SE, Keung W, Chow H, Miller AL, Leung AY, Hajjar RJ, Li RA, Chan CW. Weng Z, et al. Among authors: ren l. Stem Cells Dev. 2014 Jul 15;23(14):1704-16. doi: 10.1089/scd.2013.0509. Epub 2014 Apr 22. Stem Cells Dev. 2014. PMID: 24564569 Free PMC article.
Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs.
Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Chen G, et al. Among authors: ren l. Circ Arrhythm Electrophysiol. 2015 Feb;8(1):193-202. doi: 10.1161/CIRCEP.114.002049. Epub 2014 Dec 10. Circ Arrhythm Electrophysiol. 2015. PMID: 25504561 Free PMC article.
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, Gho JMIH, Tsiapras D, Vink A, Wu JC, Asselbergs FW, Li RA, Hulot JS, Kranias EG, Hajjar RJ. Karakikes I, et al. Among authors: ren l. Nat Commun. 2015 Apr 29;6:6955. doi: 10.1038/ncomms7955. Nat Commun. 2015. PMID: 25923014 Free PMC article.
7,143 results