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MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.
Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0. Nat Commun. 2019. PMID: 31097693 Free PMC article.
CRISPR/Cas9 for cancer research and therapy.
Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Semin Cancer Biol. 2019 Apr;55:106-119. doi: 10.1016/j.semcancer.2018.04.001. Epub 2018 Apr 16. Semin Cancer Biol. 2019. PMID: 29673923 Free article. Review.
The drug-induced phenotypic landscape of colorectal cancer organoids.
Betge J, Rindtorff N, Sauer J, Rauscher B, Dingert C, Gaitantzi H, Herweck F, Srour-Mhanna K, Miersch T, Valentini E, Boonekamp KE, Hauber V, Gutting T, Frank L, Belle S, Gaiser T, Buchholz I, Jesenofsky R, Härtel N, Zhan T, Fischer B, Breitkopf-Heinlein K, Burgermeister E, Ebert MP, Boutros M. Betge J, et al. Nat Commun. 2022 Jun 6;13(1):3135. doi: 10.1038/s41467-022-30722-9. Nat Commun. 2022. PMID: 35668108 Free PMC article.
Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors.
Bamberg LV, Heigwer F, Wandmacher AM, Singh A, Betge J, Rindtorff N, Werner J, Josten J, Skabkina OV, Hinsenkamp I, Erdmann G, Röcken C, Ebert MP, Burgermeister E, Zhan T, Boutros M. Bamberg LV, et al. Among authors: betge j. Int J Cancer. 2022 Nov 1;151(9):1586-1601. doi: 10.1002/ijc.34155. Epub 2022 Jun 28. Int J Cancer. 2022. PMID: 35666536
PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells.
Gutting T, Hauber V, Pahl J, Klapproth K, Wu W, Dobrota I, Herweck F, Reichling J, Helm L, Schroeder T, Li B, Weidner P, Zhan T, Eckardt M, Betge J, Belle S, Sticht C, Gaiser T, Boutros M, Ebert MPA, Cerwenka A, Burgermeister E. Gutting T, et al. Among authors: betge j. Oncoimmunology. 2021 May 5;10(1):1906500. doi: 10.1080/2162402X.2021.1906500. Oncoimmunology. 2021. PMID: 34026331 Free PMC article.
49 results