Digiacomo M - Search Results

1

Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma.

Tampucci S, Carpi S, Digiacomo M, Polini B, Fogli S, Burgalassi S, Macchia M, Nieri P, Manera C, Monti D. Tampucci S, et al. Among authors: digiacomo m. Molecules. 2019 May 9;24(9):1793. doi: 10.3390/molecules24091793. Molecules. 2019. PMID: 31075867 Free PMC article.

2

New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties.

Breschi MC, Calderone V, Digiacomo M, Macchia M, Martelli A, Martinotti E, Minutolo F, Rapposelli S, Rossello A, Testai L, Balsamo A. Breschi MC, et al. Among authors: digiacomo m. J Med Chem. 2006 Apr 20;49(8):2628-39. doi: 10.1021/jm0600186. J Med Chem. 2006. PMID: 16610806

3

Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs.

Minutolo F, Cascio MG, Carboni I, Bisogno T, Prota G, Bertini S, Digiacomo M, Bifulco M, Di Marzo V, Macchia M. Minutolo F, et al. Among authors: digiacomo m. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4878-81. doi: 10.1016/j.bmcl.2007.06.055. Epub 2007 Jun 20. Bioorg Med Chem Lett. 2007. PMID: 17604171

4

alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.

Asso V, Ghilardi E, Bertini S, Digiacomo M, Granchi C, Minutolo F, Rapposelli S, Bortolato A, Moro S, Macchia M. Asso V, et al. Among authors: digiacomo m. ChemMedChem. 2008 Oct;3(10):1530-4. doi: 10.1002/cmdc.200800162. ChemMedChem. 2008. PMID: 18781572 No abstract available.

5

Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells.

Fogli S, Banti I, Stefanelli F, Picchianti L, Digiacomo M, Macchia M, Breschi MC, Lapucci A. Fogli S, et al. Among authors: digiacomo m. Eur J Med Chem. 2010 Nov;45(11):5100-7. doi: 10.1016/j.ejmech.2010.08.019. Epub 2010 Aug 12. Eur J Med Chem. 2010. PMID: 20801552

6

SAR study on arylmethyloxyphenyl scaffold: looking for a P-gp nanomolar affinity.

Nesi G, Colabufo NA, Contino M, Perrone MG, Digiacomo M, Perrone R, Lapucci A, Macchia M, Rapposelli S. Nesi G, et al. Among authors: digiacomo m. Eur J Med Chem. 2014 Apr 9;76:558-66. doi: 10.1016/j.ejmech.2014.02.051. Epub 2014 Feb 21. Eur J Med Chem. 2014. PMID: 24607999

7

Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.

Digiacomo M, Chen Z, Wang S, Lapucci A, Macchia M, Yang X, Chu J, Han Y, Pi R, Rapposelli S. Digiacomo M, et al. Bioorg Med Chem Lett. 2015 Feb 15;25(4):807-10. doi: 10.1016/j.bmcl.2014.12.084. Epub 2015 Jan 6. Bioorg Med Chem Lett. 2015. PMID: 25597007

8

Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor.

Saccomanni G, Pascali G, Carlo SD, Panetta D, De Simone M, Bertini S, Burchielli S, Digiacomo M, Macchia M, Manera C, Salvadori PA. Saccomanni G, et al. Among authors: digiacomo m. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2532-5. doi: 10.1016/j.bmcl.2015.04.055. Epub 2015 Apr 25. Bioorg Med Chem Lett. 2015. PMID: 25956416

9

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme.

Sestito S, Nesi G, Daniele S, Martelli A, Digiacomo M, Borghini A, Pietra D, Calderone V, Lapucci A, Falasca M, Parrella P, Notarangelo A, Breschi MC, Macchia M, Martini C, Rapposelli S. Sestito S, et al. Among authors: digiacomo m. Eur J Med Chem. 2015 Nov 13;105:274-88. doi: 10.1016/j.ejmech.2015.10.020. Epub 2015 Oct 22. Eur J Med Chem. 2015. PMID: 26498573

10

Synthesis and In Vivo Imaging of N-(3-[¹¹C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein.

Petroni D, Bartoli A, Rapposelli S, Digiacomo M, Burchielli S, Nesi G, Lapucci A, Pardini S, Fucci S, Macchia M, Salvadori PA, Menichetti L. Petroni D, et al. Among authors: digiacomo m. Mol Imaging Biol. 2016 Dec;18(6):916-923. doi: 10.1007/s11307-016-0965-6. Mol Imaging Biol. 2016. PMID: 27234445

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