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Page 1
High-throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways.
Sachse C, Krausz E, Krönke A, Hannus M, Walsh A, Grabner A, Ovcharenko D, Dorris D, Trudel C, Sönnichsen B, Echeverri CJ. Sachse C, et al. Among authors: sonnichsen b. Methods Enzymol. 2005;392:242-77. doi: 10.1016/S0076-6879(04)92015-0. Methods Enzymol. 2005. PMID: 15644186
siRNA screen identifies QPCT as a druggable target for Huntington's disease.
Jimenez-Sanchez M, Lam W, Hannus M, Sönnichsen B, Imarisio S, Fleming A, Tarditi A, Menzies F, Dami TE, Xu C, Gonzalez-Couto E, Lazzeroni G, Heitz F, Diamanti D, Massai L, Satagopam VP, Marconi G, Caramelli C, Nencini A, Andreini M, Sardone GL, Caradonna NP, Porcari V, Scali C, Schneider R, Pollio G, O'Kane CJ, Caricasole A, Rubinsztein DC. Jimenez-Sanchez M, et al. Among authors: sonnichsen b. Nat Chem Biol. 2015 May;11(5):347-354. doi: 10.1038/nchembio.1790. Epub 2015 Apr 6. Nat Chem Biol. 2015. PMID: 25848931 Free PMC article.
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.
Sönnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Röder M, Finell J, Häntsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gönczy P, Coulson A, Hyman AA, Echeverri CJ. Sönnichsen B, et al. Nature. 2005 Mar 24;434(7032):462-9. doi: 10.1038/nature03353. Nature. 2005. PMID: 15791247
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.
Kittler R, Surendranath V, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Sönnichsen B, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B, Buchholz F. Kittler R, et al. Among authors: sonnichsen b. Nat Methods. 2007 Apr;4(4):337-44. doi: 10.1038/nmeth1025. Epub 2007 Mar 11. Nat Methods. 2007. PMID: 17351622
A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.
Bruhn S, Fang Y, Barrenäs F, Gustafsson M, Zhang H, Konstantinell A, Krönke A, Sönnichsen B, Bresnick A, Dulyaninova N, Wang H, Zhao Y, Klingelhöfer J, Ambartsumian N, Beck MK, Nestor C, Bona E, Xiang Z, Benson M. Bruhn S, et al. Among authors: sonnichsen b. Sci Transl Med. 2014 Jan 8;6(218):218ra4. doi: 10.1126/scitranslmed.3007410. Sci Transl Med. 2014. PMID: 24401939 Free PMC article.
23 results