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Page 1
HDL from an Alzheimer's disease perspective.
Button EB, Robert J, Caffrey TM, Fan J, Zhao W, Wellington CL. Button EB, et al. Among authors: wellington cl. Curr Opin Lipidol. 2019 Jun;30(3):224-234. doi: 10.1097/MOL.0000000000000604. Curr Opin Lipidol. 2019. PMID: 30946049 Free PMC article. Review.
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: wellington cl. J Biol Chem. 2005 Dec 30;280(52):43243-56. doi: 10.1074/jbc.M508781200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207707 Free article.
Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.
Burgess BL, McIsaac SA, Naus KE, Chan JY, Tansley GH, Yang J, Miao F, Ross CJ, van Eck M, Hayden MR, van Nostrand W, St George-Hyslop P, Westaway D, Wellington CL. Burgess BL, et al. Among authors: wellington cl. Neurobiol Dis. 2006 Oct;24(1):114-27. doi: 10.1016/j.nbd.2006.06.007. Epub 2006 Aug 8. Neurobiol Dis. 2006. PMID: 16899370
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, Demattos RB, Wellington CL. Burgess BL, et al. Among authors: wellington cl. J Lipid Res. 2008 Jun;49(6):1254-67. doi: 10.1194/jlr.M700481-JLR200. Epub 2008 Feb 26. J Lipid Res. 2008. PMID: 18314463 Free article.
Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice.
Burgess B, Naus K, Chan J, Hirsch-Reinshagen V, Tansley G, Matzke L, Chan B, Wilkinson A, Fan J, Donkin J, Balik D, Tanaka T, Ou G, Dyer R, Innis S, McManus B, Lütjohann D, Wellington C. Burgess B, et al. Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1731-7. doi: 10.1161/ATVBAHA.108.168542. Epub 2008 Jul 3. Arterioscler Thromb Vasc Biol. 2008. PMID: 18599800
LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Hirsch-Reinshagen V, Donkin J, Stukas S, Chan J, Wilkinson A, Fan J, Parks JS, Kuivenhoven JA, Lütjohann D, Pritchard H, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: wellington cl. J Lipid Res. 2009 May;50(5):885-93. doi: 10.1194/jlr.M800584-JLR200. Epub 2008 Dec 8. J Lipid Res. 2009. PMID: 19065001 Free PMC article.
163 results