Xiong XF - Search Results

1

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.

Niu Y, Lin Z, Wan A, Chen H, Liang H, Sun L, Wang Y, Li X, Xiong XF, Wei B, Wu X, Wan G. Niu Y, et al. Among authors: xiong xf. Mol Cancer. 2019 Mar 28;18(1):46. doi: 10.1186/s12943-019-1004-4. Mol Cancer. 2019. PMID: 30922314 Free PMC article.

2

The m⁶A demethylase FTO promotes the osteogenesis of mesenchymal stem cells by downregulating PPARG.

Chen LS, Zhang M, Chen P, Xiong XF, Liu PQ, Wang HB, Wang JJ, Shen J. Chen LS, et al. Among authors: xiong xf. Acta Pharmacol Sin. 2022 May;43(5):1311-1323. doi: 10.1038/s41401-021-00756-8. Epub 2021 Aug 30. Acta Pharmacol Sin. 2022. PMID: 34462564 Free PMC article.

3

Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis.

Song Z, Huang YY, Hou KQ, Liu L, Zhou F, Huang Y, Wan G, Luo HB, Xiong XF. Song Z, et al. Among authors: xiong xf. J Med Chem. 2022 Mar 10;65(5):4238-4254. doi: 10.1021/acs.jmedchem.1c02058. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188767

4

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer.

Luo X, Cai G, Guo Y, Gao C, Huang W, Zhang Z, Lu H, Liu K, Chen J, Xiong X, Lei J, Zhou X, Wang J, Liu Y. Luo X, et al. J Med Chem. 2021 Sep 23;64(18):13918-13932. doi: 10.1021/acs.jmedchem.1c01402. Epub 2021 Sep 13. J Med Chem. 2021. PMID: 34516133

5

Small Molecule-Inducible and Photoactivatable Cellular RNA N1-Methyladenosine Editing.

Xie G, Lu Y, He J, Yang X, Zhou J, Yi C, Li J, Li Z, Asadikaram G, Niu H, Xiong X, Li J, Wang H. Xie G, et al. Angew Chem Int Ed Engl. 2024 Jun 21;63(26):e202320029. doi: 10.1002/anie.202320029. Epub 2024 May 16. Angew Chem Int Ed Engl. 2024. PMID: 38591694

6

Therapeutic targeting ERRγ suppresses metastasis via extracellular matrix remodeling in small cell lung cancer.

Wang H, Sun H, Huang J, Zhang Z, Cai G, Wang C, Xiao K, Xiong X, Zhang J, Liu P, Lu X, Feng W, Wang J. Wang H, et al. EMBO Mol Med. 2024 Sep;16(9):2043-2059. doi: 10.1038/s44321-024-00108-z. Epub 2024 Jul 31. EMBO Mol Med. 2024. PMID: 39085398 Free PMC article.

7

GQ262 Attenuates Pathological Cardiac Remodeling by Downregulating the Akt/mTOR Signaling Pathway.

Ma H, Ge Y, Di C, Wang X, Qin B, Wang A, Hu W, Lai Z, Xiong X, Qi R. Ma H, et al. Int J Mol Sci. 2024 Sep 25;25(19):10297. doi: 10.3390/ijms251910297. Int J Mol Sci. 2024. PMID: 39408627 Free PMC article.

8

Targeting mutated GTPase KRAS in tumor therapies.

Fan G, Lou L, Song Z, Zhang X, Xiong XF. Fan G, et al. Among authors: xiong xf. Eur J Med Chem. 2021 Dec 15;226:113816. doi: 10.1016/j.ejmech.2021.113816. Epub 2021 Sep 4. Eur J Med Chem. 2021. PMID: 34520956 Review.

9

Identification of novel Pyrrolo[2,3-d]Pyrimidine-based KRAS G12C inhibitors with anticancer effects.

Song Z, Lou L, Fan G, Liu L, Ge Y, Liu H, Chan ASC, Zhang X, Xiong XF. Song Z, et al. Among authors: xiong xf. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114907. doi: 10.1016/j.ejmech.2022.114907. Epub 2022 Nov 9. Eur J Med Chem. 2023. PMID: 36395648

10

Neuropeptide Precursor VGF Promotes Liver Metastatic Colonization of Gαq Mutant Uveal Melanoma by Facilitating Tumor Microenvironment via Paracrine Loops.

Ouyang S, Shi S, Ding W, Ge Y, Su Y, Mo J, Peng K, Zhang Q, Liu G, Xiao W, Yue P, Lu J, Wang Y, Xiong X, Zhang X. Ouyang S, et al. Adv Sci (Weinh). 2024 Dec;11(46):e2407967. doi: 10.1002/advs.202407967. Epub 2024 Oct 18. Adv Sci (Weinh). 2024. PMID: 39422674 Free PMC article.

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