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Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer.
Weisner J, Landel I, Reintjes C, Uhlenbrock N, Trajkovic-Arsic M, Dienstbier N, Hardick J, Ladigan S, Lindemann M, Smith S, Quambusch L, Scheinpflug R, Depta L, Gontla R, Unger A, Müller H, Baumann M, Schultz-Fademrecht C, Günther G, Maghnouj A, Müller MP, Pohl M, Teschendorf C, Wolters H, Viebahn R, Tannapfel A, Uhl W, Hengstler JG, Hahn SA, Siveke JT, Rauh D. Weisner J, et al. Among authors: lindemann m. Cancer Res. 2019 May 1;79(9):2367-2378. doi: 10.1158/0008-5472.CAN-18-2861. Epub 2019 Mar 11. Cancer Res. 2019. PMID: 30858154
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt.
Uhlenbrock N, Smith S, Weisner J, Landel I, Lindemann M, Le TA, Hardick J, Gontla R, Scheinpflug R, Czodrowski P, Janning P, Depta L, Quambusch L, Müller MP, Engels B, Rauh D. Uhlenbrock N, et al. Among authors: lindemann m. Chem Sci. 2019 Feb 13;10(12):3573-3585. doi: 10.1039/c8sc05212c. eCollection 2019 Mar 28. Chem Sci. 2019. PMID: 30996949 Free PMC article.
Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach.
van der Westhuizen L, Weisner J, Taher A, Landel I, Quambusch L, Lindemann M, Uhlenbrock N, Müller MP, Green IR, Pelly SC, Rauh D, van Otterlo WAL. van der Westhuizen L, et al. Among authors: lindemann m. ChemMedChem. 2022 May 18;17(10):e202100776. doi: 10.1002/cmdc.202100776. Epub 2022 Mar 9. ChemMedChem. 2022. PMID: 35170857 Free PMC article.
Risk Stratification Before Living Donor Kidney Transplantation in Patients With Preformed Donor-specific Antibodies by Different Crossmatch Methods.
Ziemann M, Lindemann M, Hallensleben M, Altermann W, Althaus K, Budde K, Einecke G, Eisenberger U, Ender A, Feldkamp T, Grahammer F, Guthoff M, Holzmann-Littig C, Hugo C, Kauke T, Kemmner S, Koch M, Lachmann N, Marget M, Morath C, Nitschke M, Renders L, Scherer S, Stumpf J, Schwenger V, Sommer F, Spriewald B, Süsal C, Zecher D, Heinemann FM, Verboom M. Ziemann M, et al. Among authors: lindemann m. Transplant Direct. 2024 Aug 8;10(9):e1680. doi: 10.1097/TXD.0000000000001680. eCollection 2024 Sep. Transplant Direct. 2024. PMID: 39131238 Free PMC article.
Liquid Biopsy in Whole Blood for Identification of Gene Expression Patterns (mRNA and miRNA) Associated with Recurrence of Glioblastoma WHO CNS Grade 4.
Muhtadi R, Bernhardt D, Multhoff G, Hönikl L, Combs SE, Krieg SM, Gempt J, Meyer B, Barsegian V, Lindemann M, Kasper M, Stewart S, Port M, Abend M, Diehl CD, Ostheim P. Muhtadi R, et al. Among authors: lindemann m. Cancers (Basel). 2024 Jun 26;16(13):2345. doi: 10.3390/cancers16132345. Cancers (Basel). 2024. PMID: 39001407 Free PMC article.
410 results