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Diversifying the structure of zinc finger nucleases for high-precision genome editing.
Paschon DE, Lussier S, Wangzor T, Xia DF, Li PW, Hinkley SJ, Scarlott NA, Lam SC, Waite AJ, Truong LN, Gandhi N, Kadam BN, Patil DP, Shivak DA, Lee GK, Holmes MC, Zhang L, Miller JC, Rebar EJ. Paschon DE, et al. Among authors: holmes mc. Nat Commun. 2019 Mar 8;10(1):1133. doi: 10.1038/s41467-019-08867-x. Nat Commun. 2019. PMID: 30850604 Free PMC article.
An improved zinc-finger nuclease architecture for highly specific genome editing.
Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ. Miller JC, et al. Among authors: holmes mc. Nat Biotechnol. 2007 Jul;25(7):778-85. doi: 10.1038/nbt1319. Epub 2007 Jul 1. Nat Biotechnol. 2007. PMID: 17603475
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.
Santiago Y, Chan E, Liu PQ, Orlando S, Zhang L, Urnov FD, Holmes MC, Guschin D, Waite A, Miller JC, Rebar EJ, Gregory PD, Klug A, Collingwood TN. Santiago Y, et al. Among authors: holmes mc. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5809-14. doi: 10.1073/pnas.0800940105. Epub 2008 Mar 21. Proc Natl Acad Sci U S A. 2008. PMID: 18359850 Free PMC article.
Genome editing with engineered zinc finger nucleases.
Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD. Urnov FD, et al. Among authors: holmes mc. Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Nat Rev Genet. 2010. PMID: 20717154 Review.
A TALE nuclease architecture for efficient genome editing.
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ. Miller JC, et al. Among authors: holmes mc. Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22. Nat Biotechnol. 2011. PMID: 21179091
Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets.
Conway A, Mendel M, Kim K, McGovern K, Boyko A, Zhang L, Miller JC, DeKelver RC, Paschon DE, Mui BL, Lin PJC, Tam YK, Barbosa C, Redelmeier T, Holmes MC, Lee G. Conway A, et al. Among authors: holmes mc. Mol Ther. 2019 Apr 10;27(4):866-877. doi: 10.1016/j.ymthe.2019.03.003. Epub 2019 Mar 7. Mol Ther. 2019. PMID: 30902585 Free PMC article.
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases.
Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, Liu O, Wang N, Lee G, Bartsevich VV, Lee YL, Guschin DY, Rupniewski I, Waite AJ, Carpenito C, Carroll RG, Orange JS, Urnov FD, Rebar EJ, Ando D, Gregory PD, Riley JL, Holmes MC, June CH. Perez EE, et al. Among authors: holmes mc. Nat Biotechnol. 2008 Jul;26(7):808-16. doi: 10.1038/nbt1410. Epub 2008 Jun 29. Nat Biotechnol. 2008. PMID: 18587387 Free PMC article.
230 results