Lawlor KT - Search Results

1

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells.

Kumar SV, Er PX, Lawlor KT, Motazedian A, Scurr M, Ghobrial I, Combes AN, Zappia L, Oshlack A, Stanley EG, Little MH. Kumar SV, et al. Among authors: lawlor kt. Development. 2019 Mar 7;146(5):dev172361. doi: 10.1242/dev.172361. Development. 2019. PMID: 30846463 Free PMC article.

2

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening.

Hale LJ, Howden SE, Phipson B, Lonsdale A, Er PX, Ghobrial I, Hosawi S, Wilson S, Lawlor KT, Khan S, Oshlack A, Quinlan C, Lennon R, Little MH. Hale LJ, et al. Among authors: lawlor kt. Nat Commun. 2018 Dec 4;9(1):5167. doi: 10.1038/s41467-018-07594-z. Nat Commun. 2018. PMID: 30514835 Free PMC article.

3

Evaluation of variability in human kidney organoids.

Phipson B, Er PX, Combes AN, Forbes TA, Howden SE, Zappia L, Yen HJ, Lawlor KT, Hale LJ, Sun J, Wolvetang E, Takasato M, Oshlack A, Little MH. Phipson B, et al. Among authors: lawlor kt. Nat Methods. 2019 Jan;16(1):79-87. doi: 10.1038/s41592-018-0253-2. Epub 2018 Dec 20. Nat Methods. 2019. PMID: 30573816 Free PMC article.

4

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk.

Combes AN, Phipson B, Lawlor KT, Dorison A, Patrick R, Zappia L, Harvey RP, Oshlack A, Little MH. Combes AN, et al. Among authors: lawlor kt. Development. 2019 Jun 12;146(12):dev178673. doi: 10.1242/dev.178673. Development. 2019. PMID: 31118232

5

Recreating, expanding and using nephron progenitor populations.

Little MH, Lawlor KT. Little MH, et al. Among authors: lawlor kt. Nat Rev Nephrol. 2020 Feb;16(2):75-76. doi: 10.1038/s41581-019-0238-0. Nat Rev Nephrol. 2020. PMID: 31811252 Free PMC article. Review.

6

Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.

Forbes TA, Howden SE, Lawlor K, Phipson B, Maksimovic J, Hale L, Wilson S, Quinlan C, Ho G, Holman K, Bennetts B, Crawford J, Trnka P, Oshlack A, Patel C, Mallett A, Simons C, Little MH. Forbes TA, et al. Am J Hum Genet. 2018 May 3;102(5):816-831. doi: 10.1016/j.ajhg.2018.03.014. Epub 2018 Apr 26. Am J Hum Genet. 2018. PMID: 29706353 Free PMC article.

7

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number.

Combes AN, Wilson S, Phipson B, Binnie BB, Ju A, Lawlor KT, Cebrian C, Walton SL, Smyth IM, Moritz KM, Kopan R, Oshlack A, Little MH. Combes AN, et al. Among authors: lawlor kt. Kidney Int. 2018 Mar;93(3):589-598. doi: 10.1016/j.kint.2017.09.015. Epub 2017 Dec 6. Kidney Int. 2018. PMID: 29217079 Free PMC article.

8

Nephron progenitor commitment is a stochastic process influenced by cell migration.

Lawlor KT, Zappia L, Lefevre J, Park JS, Hamilton NA, Oshlack A, Little MH, Combes AN. Lawlor KT, et al. Elife. 2019 Jan 24;8:e41156. doi: 10.7554/eLife.41156. Elife. 2019. PMID: 30676318 Free PMC article.

9

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation.

Lawlor KT, Vanslambrouck JM, Higgins JW, Chambon A, Bishard K, Arndt D, Er PX, Wilson SB, Howden SE, Tan KS, Li F, Hale LJ, Shepherd B, Pentoney S, Presnell SC, Chen AE, Little MH. Lawlor KT, et al. Nat Mater. 2021 Feb;20(2):260-271. doi: 10.1038/s41563-020-00853-9. Epub 2020 Nov 23. Nat Mater. 2021. PMID: 33230326 Free PMC article.

10

Determining lineage relationships in kidney development and disease.

Little MH, Howden SE, Lawlor KT, Vanslambrouck JM. Little MH, et al. Among authors: lawlor kt. Nat Rev Nephrol. 2022 Jan;18(1):8-21. doi: 10.1038/s41581-021-00485-5. Epub 2021 Sep 30. Nat Rev Nephrol. 2022. PMID: 34594045 Review.

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