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DNA stretching induces Cas9 off-target activity.
Newton MD, Taylor BJ, Driessen RPC, Roos L, Cvetesic N, Allyjaun S, Lenhard B, Cuomo ME, Rueda DS. Newton MD, et al. Among authors: rueda ds. Nat Struct Mol Biol. 2019 Mar;26(3):185-192. doi: 10.1038/s41594-019-0188-z. Epub 2019 Feb 25. Nat Struct Mol Biol. 2019. PMID: 30804513 Free PMC article.
A high-resolution map of transcriptional repression.
Liang Z, Brown KE, Carroll T, Taylor B, Vidal IF, Hendrich B, Rueda D, Fisher AG, Merkenschlager M. Liang Z, et al. Elife. 2017 Mar 20;6:e22767. doi: 10.7554/eLife.22767. Elife. 2017. PMID: 28318487 Free PMC article.
A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules.
Gutierrez-Escribano P, Newton MD, Llauró A, Huber J, Tanasie L, Davy J, Aly I, Aramayo R, Montoya A, Kramer H, Stigler J, Rueda DS, Aragon L. Gutierrez-Escribano P, et al. Among authors: rueda ds. Sci Adv. 2019 Nov 27;5(11):eaay6804. doi: 10.1126/sciadv.aay6804. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807710 Free PMC article.
95 results