Lowman XH - Search Results

1

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.

Yang Y, Ishak Gabra MB, Hanse EA, Lowman XH, Tran TQ, Li H, Milman N, Liu J, Reid MA, Locasale JW, Gil Z, Kong M. Yang Y, et al. Among authors: lowman xh. Nat Commun. 2019 Feb 18;10(1):809. doi: 10.1038/s41467-019-08759-0. Nat Commun. 2019. PMID: 30778058 Free PMC article.

2

Vemurafenib resistance reprograms melanoma cells towards glutamine dependence.

Hernandez-Davies JE, Tran TQ, Reid MA, Rosales KR, Lowman XH, Pan M, Moriceau G, Yang Y, Wu J, Lo RS, Kong M. Hernandez-Davies JE, et al. Among authors: lowman xh. J Transl Med. 2015 Jul 3;13:210. doi: 10.1186/s12967-015-0581-2. J Transl Med. 2015. PMID: 26139106 Free PMC article.

3

TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.

Rosales KR, Reid MA, Yang Y, Tran TQ, Wang WI, Lowman X, Pan M, Kong M. Rosales KR, et al. PLoS One. 2015 Dec 30;10(12):e0145938. doi: 10.1371/journal.pone.0145938. eCollection 2015. PLoS One. 2015. PMID: 26717153 Free PMC article.

4

Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells.

Yan Y, Hanse EA, Stedman K, Benson JM, Lowman XH, Subramanian S, Kelekar A. Yan Y, et al. Among authors: lowman xh. Cell Death Differ. 2016 Jul;23(7):1232-42. doi: 10.1038/cdd.2016.1. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868909 Free PMC article.

5

IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.

Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Reid MA, et al. Among authors: lowman xh. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. Genes Dev. 2016. PMID: 27585591 Free PMC article.

6

Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.

Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, Gradinaru V, Lo RS, Locasale JW, Kong M. Pan M, et al. Among authors: lowman xh. Nat Cell Biol. 2016 Oct;18(10):1090-101. doi: 10.1038/ncb3410. Epub 2016 Sep 12. Nat Cell Biol. 2016. PMID: 27617932 Free PMC article.

7

Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction.

Tran TQ, Lowman XH, Reid MA, Mendez-Dorantes C, Pan M, Yang Y, Kong M. Tran TQ, et al. Among authors: lowman xh. Oncogene. 2017 Apr 6;36(14):1991-2001. doi: 10.1038/onc.2016.360. Epub 2016 Oct 10. Oncogene. 2017. PMID: 27721412 Free PMC article.

8

Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer.

Hanse EA, Ruan C, Kachman M, Wang D, Lowman XH, Kelekar A. Hanse EA, et al. Among authors: lowman xh. Oncogene. 2017 Jul 6;36(27):3915-3924. doi: 10.1038/onc.2017.36. Epub 2017 Mar 6. Oncogene. 2017. PMID: 28263970 Free PMC article.

9

Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.

Tran TQ, Lowman XH, Kong M. Tran TQ, et al. Among authors: lowman xh. Clin Cancer Res. 2017 Aug 1;23(15):4004-4009. doi: 10.1158/1078-0432.CCR-16-2506. Epub 2017 Apr 12. Clin Cancer Res. 2017. PMID: 28404599 Free PMC article. Review.

10

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes.

Tran TQ, Ishak Gabra MB, Lowman XH, Yang Y, Reid MA, Pan M, O'Connor TR, Kong M. Tran TQ, et al. Among authors: lowman xh. PLoS Biol. 2017 Nov 6;15(11):e2002810. doi: 10.1371/journal.pbio.2002810. eCollection 2017 Nov. PLoS Biol. 2017. PMID: 29107960 Free PMC article.

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