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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.
Du H, Hirabayashi K, Ahn S, Kren NP, Montgomery SA, Wang X, Tiruthani K, Mirlekar B, Michaud D, Greene K, Herrera SG, Xu Y, Sun C, Chen Y, Ma X, Ferrone CR, Pylayeva-Gupta Y, Yeh JJ, Liu R, Savoldo B, Ferrone S, Dotti G. Du H, et al. Cancer Cell. 2019 Feb 11;35(2):221-237.e8. doi: 10.1016/j.ccell.2019.01.002. Cancer Cell. 2019. PMID: 30753824 Free PMC article.
Interleukin-23 engineering improves CAR T cell function in solid tumors.
Ma X, Shou P, Smith C, Chen Y, Du H, Sun C, Porterfield Kren N, Michaud D, Ahn S, Vincent B, Savoldo B, Pylayeva-Gupta Y, Zhang S, Dotti G, Xu Y. Ma X, et al. Nat Biotechnol. 2020 Apr;38(4):448-459. doi: 10.1038/s41587-019-0398-2. Epub 2020 Feb 3. Nat Biotechnol. 2020. PMID: 32015548 Free PMC article.
B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer.
Mirlekar B, Michaud D, Lee SJ, Kren NP, Harris C, Greene K, Goldman EC, Gupta GP, Fields RC, Hawkins WG, DeNardo DG, Rashid NU, Yeh JJ, McRee AJ, Vincent BG, Vignali DAA, Pylayeva-Gupta Y. Mirlekar B, et al. Cancer Immunol Res. 2020 Mar;8(3):292-308. doi: 10.1158/2326-6066.CIR-19-0349. Epub 2020 Feb 5. Cancer Immunol Res. 2020. PMID: 32024640 Free PMC article.
Regulatory B cells in cancer.
Michaud D, Steward CR, Mirlekar B, Pylayeva-Gupta Y. Michaud D, et al. Among authors: pylayeva gupta y. Immunol Rev. 2021 Jan;299(1):74-92. doi: 10.1111/imr.12939. Epub 2020 Dec 23. Immunol Rev. 2021. PMID: 33368346 Free PMC article. Review.
IL-35 Detection in B Cells at the mRNA and Protein Level.
Mirlekar B, Michaud D, Pylayeva-Gupta Y. Mirlekar B, et al. Among authors: pylayeva gupta y. Methods Mol Biol. 2021;2270:125-147. doi: 10.1007/978-1-0716-1237-8_8. Methods Mol Biol. 2021. PMID: 33479897
Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity.
Mirlekar B, Wang Y, Li S, Zhou M, Entwistle S, De Buysscher T, Morrison A, Herrera G, Harris C, Vincent BG, Ting JP, Rashid N, Kim WY, Yeh JJ, Pylayeva-Gupta Y. Mirlekar B, et al. Among authors: pylayeva gupta y. Cell Rep Med. 2022 Sep 20;3(9):100744. doi: 10.1016/j.xcrm.2022.100744. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099917 Free PMC article.
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