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Page 1
Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects.
Baudy AR, Reeves EK, Damsker JM, Heier C, Garvin LM, Dillingham BC, McCall J, Rayavarapu S, Wang Z, Vandermeulen JH, Sali A, Jahnke V, Duguez S, DuBois D, Rose MC, Nagaraju K, Hoffman EP. Baudy AR, et al. J Pharmacol Exp Ther. 2012 Oct;343(1):225-32. doi: 10.1124/jpet.112.194340. Epub 2012 Jun 28. J Pharmacol Exp Ther. 2012. PMID: 22743576 Free PMC article.
VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice.
Damsker JM, Dillingham BC, Rose MC, Balsley MA, Heier CR, Watson AM, Stemmy EJ, Jurjus RA, Huynh T, Tatem K, Uaesoontrachoon K, Berry DM, Benton AS, Freishtat RJ, Hoffman EP, McCall JM, Gordish-Dressman H, Constant SL, Reeves EK, Nagaraju K. Damsker JM, et al. Among authors: heier cr. PLoS One. 2013 May 7;8(5):e63871. doi: 10.1371/journal.pone.0063871. Print 2013. PLoS One. 2013. PMID: 23667681 Free PMC article.
VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects.
Heier CR, Damsker JM, Yu Q, Dillingham BC, Huynh T, Van der Meulen JH, Sali A, Miller BK, Phadke A, Scheffer L, Quinn J, Tatem K, Jordan S, Dadgar S, Rodriguez OC, Albanese C, Calhoun M, Gordish-Dressman H, Jaiswal JK, Connor EM, McCall JM, Hoffman EP, Reeves EK, Nagaraju K. Heier CR, et al. EMBO Mol Med. 2013 Oct;5(10):1569-85. doi: 10.1002/emmm.201302621. Epub 2013 Sep 9. EMBO Mol Med. 2013. PMID: 24014378 Free PMC article.
TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy.
Fiorillo AA, Heier CR, Novak JS, Tully CB, Brown KJ, Uaesoontrachoon K, Vila MC, Ngheim PP, Bello L, Kornegay JN, Angelini C, Partridge TA, Nagaraju K, Hoffman EP. Fiorillo AA, et al. Among authors: heier cr. Cell Rep. 2015 Sep 8;12(10):1678-90. doi: 10.1016/j.celrep.2015.07.066. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321630 Free PMC article.
Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.
Hathout Y, Conklin LS, Seol H, Gordish-Dressman H, Brown KJ, Morgenroth LP, Nagaraju K, Heier CR, Damsker JM, van den Anker JN, Henricson E, Clemens PR, Mah JK, McDonald C, Hoffman EP. Hathout Y, et al. Among authors: heier cr. Sci Rep. 2016 Aug 17;6:31727. doi: 10.1038/srep31727. Sci Rep. 2016. PMID: 27530235 Free PMC article.
29 results