Blacklow SC - Search Results

1

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB. Petrovic J, et al. Among authors: blacklow sc. Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7. Mol Cell. 2019. PMID: 30745086 Free PMC article.

2

The folding and structural integrity of the first LIN-12 module of human Notch1 are calcium-dependent.

Aster JC, Simms WB, Zavala-Ruiz Z, Patriub V, North CL, Blacklow SC. Aster JC, et al. Among authors: blacklow sc. Biochemistry. 1999 Apr 13;38(15):4736-42. doi: 10.1021/bi982713o. Biochemistry. 1999. PMID: 10200161

3

Calcium depletion dissociates and activates heterodimeric notch receptors.

Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, Aster JC. Rand MD, et al. Among authors: blacklow sc. Mol Cell Biol. 2000 Mar;20(5):1825-35. doi: 10.1128/MCB.20.5.1825-1835.2000. Mol Cell Biol. 2000. PMID: 10669757 Free PMC article.

4

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD. Wu L, et al. Among authors: blacklow sc. Nat Genet. 2000 Dec;26(4):484-9. doi: 10.1038/82644. Nat Genet. 2000. PMID: 11101851

5

Notch signaling as a therapeutic target.

Nam Y, Aster JC, Blacklow SC. Nam Y, et al. Among authors: blacklow sc. Curr Opin Chem Biol. 2002 Aug;6(4):501-9. doi: 10.1016/s1367-5931(02)00346-0. Curr Opin Chem Biol. 2002. PMID: 12133727 Review.

6

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.

Weng AP, Nam Y, Wolfe MS, Pear WS, Griffin JD, Blacklow SC, Aster JC. Weng AP, et al. Among authors: blacklow sc. Mol Cell Biol. 2003 Jan;23(2):655-64. doi: 10.1128/MCB.23.2.655-664.2003. Mol Cell Biol. 2003. PMID: 12509463 Free PMC article.

7

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.

Nam Y, Weng AP, Aster JC, Blacklow SC. Nam Y, et al. Among authors: blacklow sc. J Biol Chem. 2003 Jun 6;278(23):21232-9. doi: 10.1074/jbc.M301567200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12644465 Free article.

8

Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1.

Vardar D, North CL, Sanchez-Irizarry C, Aster JC, Blacklow SC. Vardar D, et al. Among authors: blacklow sc. Biochemistry. 2003 Jun 17;42(23):7061-7. doi: 10.1021/bi034156y. Biochemistry. 2003. PMID: 12795601

9

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.

Weng AP, Ferrando AA, Lee W, Morris JP 4th, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC. Weng AP, et al. Among authors: blacklow sc. Science. 2004 Oct 8;306(5694):269-71. doi: 10.1126/science.1102160. Science. 2004. PMID: 15472075

10

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats.

Sanchez-Irizarry C, Carpenter AC, Weng AP, Pear WS, Aster JC, Blacklow SC. Sanchez-Irizarry C, et al. Among authors: blacklow sc. Mol Cell Biol. 2004 Nov;24(21):9265-73. doi: 10.1128/MCB.24.21.9265-9273.2004. Mol Cell Biol. 2004. PMID: 15485896 Free PMC article.

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