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A review of GI conditions critical to oral drug absorption in malnourished children.
Eur J Pharm Biopharm. 2019 Apr;137:9-22. doi: 10.1016/j.ejpb.2019.02.001. Epub 2019 Feb 5.
Eur J Pharm Biopharm. 2019.
PMID: 30735799
Free article.
Review.
Safe, swallowable and palatable paediatric mini-tablet formulations for a WHO model list of essential medicines for children compound - A promising starting point for future PUMA applications.
Freerks L, Sommerfeldt J, Löper PC, Klein S.
Freerks L, et al.
Eur J Pharm Biopharm. 2020 Nov;156:11-19. doi: 10.1016/j.ejpb.2020.08.014. Epub 2020 Aug 29.
Eur J Pharm Biopharm. 2020.
PMID: 32871197
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A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles.
Wollmer E, Karkossa F, Freerks L, Hetberg AE, Neal G, Porter J, Whitaker MJ, Margetson D, Klein S.
Wollmer E, et al. Among authors: freerks l.
Pharm Res. 2020 Sep 24;37(10):203. doi: 10.1007/s11095-020-02912-x.
Pharm Res. 2020.
PMID: 32968894
Free PMC article.
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A Toolbox for Mimicking Gastrointestinal Conditions in Children: Simulated Paediatric Breakfast Media (SPBM) for Addressing the Variability of Gastric Contents After Typical Paediatric Breakfasts.
Freerks L, Zielke C, Tarnow MJ, Arien T, Mackie C, Inghelbrecht S, Klein S.
Freerks L, et al.
J Pharm Sci. 2022 Jan;111(1):51-61. doi: 10.1016/j.xphs.2021.05.003. Epub 2021 May 19.
J Pharm Sci. 2022.
PMID: 34019904
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Vehicles for Drug Administration to Children: Results and Learnings from an In-Depth Screening of FDA-Recommended Liquids and Soft Foods for Product Quality Assessment.
Freerks L, Sucher W, Tarnow MJ, Eckert C, Klein S.
Freerks L, et al.
Pharm Res. 2022 Mar;39(3):497-509. doi: 10.1007/s11095-022-03208-y. Epub 2022 Mar 1.
Pharm Res. 2022.
PMID: 35233727
Free PMC article.
Review.
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A toolbox for mimicking gastrointestinal conditions in children: Design and evaluation of biorelevant dissolution media for mimicking paediatric gastric- and small intestinal conditions.
Freerks L, Arien T, Mackie C, Inghelbrecht S, Klein S.
Freerks L, et al.
Eur J Pharm Biopharm. 2023 Dec;193:144-157. doi: 10.1016/j.ejpb.2023.10.011. Epub 2023 Oct 16.
Eur J Pharm Biopharm. 2023.
PMID: 37852543
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