Park HK - Search Results

1

Interplay between TRAP1 and Sirtuin-3 Modulates Mitochondrial Respiration and Oxidative Stress to Maintain Stemness of Glioma Stem Cells.

Park HK, Hong JH, Oh YT, Kim SS, Yin J, Lee AJ, Chae YC, Kim JH, Park SH, Park CK, Park MJ, Park JB, Kang BH. Park HK, et al. Among authors: park mj, park ck, park jb, park sh. Cancer Res. 2019 Apr 1;79(7):1369-1382. doi: 10.1158/0008-5472.CAN-18-2558. Epub 2019 Jan 25. Cancer Res. 2019. PMID: 30683653

2

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells.

Park HK, Lee JE, Lim J, Kang BH. Park HK, et al. Mol Cancer. 2014 Jun 12;13:148. doi: 10.1186/1476-4598-13-148. Mol Cancer. 2014. PMID: 24924916 Free PMC article.

3

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1.

Park HK, Yoon NG, Lee JE, Hu S, Yoon S, Kim SY, Hong JH, Nam D, Chae YC, Park JB, Kang BH. Park HK, et al. Among authors: park jb. Exp Mol Med. 2020 Jan;52(1):79-91. doi: 10.1038/s12276-019-0360-x. Epub 2020 Jan 20. Exp Mol Med. 2020. PMID: 31956271 Free PMC article.

4

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.

Park HK, Lee JE, Lim J, Jo DE, Park SA, Suh PG, Kang BH. Park HK, et al. Among authors: park sa. BMC Cancer. 2014 Jun 13;14:431. doi: 10.1186/1471-2407-14-431. BMC Cancer. 2014. PMID: 24927938 Free PMC article.

5

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.

Park HK, Jeong H, Ko E, Lee G, Lee JE, Lee SK, Lee AJ, Im JY, Hu S, Kim SH, Lee JH, Lee C, Kang S, Kang BH. Park HK, et al. J Med Chem. 2017 Sep 14;60(17):7569-7578. doi: 10.1021/acs.jmedchem.7b00978. Epub 2017 Aug 30. J Med Chem. 2017. PMID: 28816449

6

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.

Lee C, Park HK, Jeong H, Lim J, Lee AJ, Cheon KY, Kim CS, Thomas AP, Bae B, Kim ND, Kim SH, Suh PG, Ryu JH, Kang BH. Lee C, et al. Among authors: park hk. J Am Chem Soc. 2015 Apr 8;137(13):4358-67. doi: 10.1021/ja511893n. Epub 2015 Mar 30. J Am Chem Soc. 2015. PMID: 25785725

7

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca²⁺ homeostasis.

Choi SS, Lee SK, Kim JK, Park HK, Lee E, Jang J, Lee YH, Khim KW, Hyun JM, Eom HJ, Lee S, Kang BH, Chae YC, Myung K, Myung SJ, Park CY, Choi JH. Choi SS, et al. Among authors: park cy, park hk. Exp Mol Med. 2020 Jun;52(6):940-950. doi: 10.1038/s12276-020-0448-3. Epub 2020 Jun 5. Exp Mol Med. 2020. PMID: 32504039 Free PMC article.

8

TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling.

Lee HH, Jeong GW, Ye BJ, Yoo EJ, Son KS, Kim DK, Park HK, Kang BH, Lee-Kwon W, Kwon HM, Choi SY. Lee HH, et al. Among authors: park hk. Diabetes. 2022 Dec 1;71(12):2557-2571. doi: 10.2337/db21-1099. Diabetes. 2022. PMID: 36170666 Free PMC article.

9

PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-β3 (PLC-β3)-specific activation of somatostatin by forming a ternary complex with PLC-β3 and somatostatin receptors.

Kim JK, Kwon O, Kim J, Kim EK, Park HK, Lee JE, Kim KL, Choi JW, Lim S, Seok H, Lee-Kwon W, Choi JH, Kang BH, Kim S, Ryu SH, Suh PG. Kim JK, et al. Among authors: park hk. J Biol Chem. 2012 Jun 15;287(25):21012-24. doi: 10.1074/jbc.M111.337865. Epub 2012 Apr 23. J Biol Chem. 2012. PMID: 22528496 Free PMC article.

10

Cloning and expression of Ca2+-activated chloride channel from rat brain.

Jeong SM, Park HK, Yoon IS, Lee JH, Kim JH, Jang CG, Lee CJ, Nah SY. Jeong SM, et al. Among authors: park hk. Biochem Biophys Res Commun. 2005 Aug 26;334(2):569-76. doi: 10.1016/j.bbrc.2005.06.122. Biochem Biophys Res Commun. 2005. PMID: 16023076

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