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Page 1
Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Beckmann PJ, Larson JD, Larsson AT, Ostergaard JP, Wagner S, Rahrmann EP, Shamsan GA, Otto GM, Williams RL, Wang J, Lee C, Tschida BR, Das P, Dubuc AM, Moriarity BS, Picard D, Wu X, Rodriguez FJ, Rosemarie Q, Krebs RD, Molan AM, Demer AM, Frees MM, Rizzardi AE, Schmechel SC, Eberhart CG, Jenkins RB, Wechsler-Reya RJ, Odde DJ, Huang A, Taylor MD, Sarver AL, Largaespada DA. Beckmann PJ, et al. Among authors: molan am. Cancer Res. 2019 Mar 1;79(5):905-917. doi: 10.1158/0008-5472.CAN-18-1261. Epub 2019 Jan 23. Cancer Res. 2019. PMID: 30674530 Free PMC article.
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.
Leonard B, McCann JL, Starrett GJ, Kosyakovsky L, Luengas EM, Molan AM, Burns MB, McDougle RM, Parker PJ, Brown WL, Harris RS. Leonard B, et al. Among authors: molan am. Cancer Res. 2015 Nov 1;75(21):4538-47. doi: 10.1158/0008-5472.CAN-15-2171-T. Epub 2015 Sep 29. Cancer Res. 2015. PMID: 26420215 Free PMC article.
Suboptimal T-cell Therapy Drives a Tumor Cell Mutator Phenotype That Promotes Escape from First-Line Treatment.
Evgin L, Huff AL, Kottke T, Thompson J, Molan AM, Driscoll CB, Schuelke M, Shim KG, Wongthida P, Ilett EJ, Smith KK, Harris RS, Coffey M, Pulido JS, Pandha H, Selby PJ, Harrington KJ, Melcher A, Vile RG. Evgin L, et al. Among authors: molan am. Cancer Immunol Res. 2019 May;7(5):828-840. doi: 10.1158/2326-6066.CIR-18-0013. Epub 2019 Apr 2. Cancer Immunol Res. 2019. PMID: 30940643 Free PMC article.
HIV-1 restriction by endogenous APOBEC3G in the myeloid cell line THP-1.
Ikeda T, Molan AM, Jarvis MC, Carpenter MA, Salamango DJ, Brown WL, Harris RS. Ikeda T, et al. Among authors: molan am. J Gen Virol. 2019 Jul;100(7):1140-1152. doi: 10.1099/jgv.0.001276. Epub 2019 May 30. J Gen Virol. 2019. PMID: 31145054 Free PMC article.
APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy.
Driscoll CB, Schuelke MR, Kottke T, Thompson JM, Wongthida P, Tonne JM, Huff AL, Miller A, Shim KG, Molan A, Wetmore C, Selby P, Samson A, Harrington K, Pandha H, Melcher A, Pulido JS, Harris R, Evgin L, Vile RG. Driscoll CB, et al. Nat Commun. 2020 Feb 7;11(1):790. doi: 10.1038/s41467-020-14568-7. Nat Commun. 2020. PMID: 32034147 Free PMC article.
APOBEC3 Mediates Resistance to Oncolytic Viral Therapy.
Huff AL, Wongthida P, Kottke T, Thompson JM, Driscoll CB, Schuelke M, Shim KG, Harris RS, Molan A, Pulido JS, Selby PJ, Harrington KJ, Melcher A, Evgin L, Vile RG. Huff AL, et al. Mol Ther Oncolytics. 2018 Aug 29;11:1-13. doi: 10.1016/j.omto.2018.08.003. eCollection 2018 Dec 21. Mol Ther Oncolytics. 2018. PMID: 30294666 Free PMC article.
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