Arun G - Search Results

1

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1.

Abulwerdi FA, Xu W, Ageeli AA, Yonkunas MJ, Arun G, Nam H, Schneekloth JS Jr, Dayie TK, Spector D, Baird N, Le Grice SFJ. Abulwerdi FA, et al. Among authors: arun g. ACS Chem Biol. 2019 Feb 15;14(2):223-235. doi: 10.1021/acschembio.8b00807. Epub 2019 Jan 31. ACS Chem Biol. 2019. PMID: 30620551 Free PMC article.

2

MALAT1 long non-coding RNA and breast cancer.

Arun G, Spector DL. Arun G, et al. RNA Biol. 2019 Jun;16(6):860-863. doi: 10.1080/15476286.2019.1592072. Epub 2019 Mar 22. RNA Biol. 2019. PMID: 30874469 Free PMC article.

3

The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult.

Zhang B, Arun G, Mao YS, Lazar Z, Hung G, Bhattacharjee G, Xiao X, Booth CJ, Wu J, Zhang C, Spector DL. Zhang B, et al. Among authors: arun g. Cell Rep. 2012 Jul 26;2(1):111-23. doi: 10.1016/j.celrep.2012.06.003. Epub 2012 Jun 28. Cell Rep. 2012. PMID: 22840402 Free PMC article.

4

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Arun G, Diermeier S, Akerman M, Chang KC, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL. Arun G, et al. Genes Dev. 2016 Jan 1;30(1):34-51. doi: 10.1101/gad.270959.115. Epub 2015 Dec 23. Genes Dev. 2016. PMID: 26701265 Free PMC article.

5

Therapeutic Targeting of Long Non-Coding RNAs in Cancer.

Arun G, Diermeier SD, Spector DL. Arun G, et al. Trends Mol Med. 2018 Mar;24(3):257-277. doi: 10.1016/j.molmed.2018.01.001. Epub 2018 Feb 12. Trends Mol Med. 2018. PMID: 29449148 Free PMC article. Review.

6

MALAT1 Long Non-Coding RNA: Functional Implications.

Arun G, Aggarwal D, Spector DL. Arun G, et al. Noncoding RNA. 2020 Jun 3;6(2):22. doi: 10.3390/ncrna6020022. Noncoding RNA. 2020. PMID: 32503170 Free PMC article. Review.

7

The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells.

Gutschner T, Hämmerle M, Eissmann M, Hsu J, Kim Y, Hung G, Revenko A, Arun G, Stentrup M, Gross M, Zörnig M, MacLeod AR, Spector DL, Diederichs S. Gutschner T, et al. Among authors: arun g. Cancer Res. 2013 Feb 1;73(3):1180-9. doi: 10.1158/0008-5472.CAN-12-2850. Epub 2012 Dec 14. Cancer Res. 2013. PMID: 23243023 Free PMC article.

8

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR. Huang YH, et al. Among authors: arun g. Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26. Genes Dev. 2018. PMID: 29945888 Free PMC article.

9

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing.

Aganezov S, Goodwin S, Sherman RM, Sedlazeck FJ, Arun G, Bhatia S, Lee I, Kirsche M, Wappel R, Kramer M, Kostroff K, Spector DL, Timp W, McCombie WR, Schatz MC. Aganezov S, et al. Among authors: arun g. Genome Res. 2020 Sep;30(9):1258-1273. doi: 10.1101/gr.260497.119. Epub 2020 Sep 4. Genome Res. 2020. PMID: 32887686 Free PMC article.

10

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics.

Bhatia S, Kramer M, Russo S, Naik P, Arun G, Brophy K, Andrews P, Fan C, Perou CM, Preall J, Ha T, Plenker D, Tuveson DA, Rishi A, Wilkinson JE, McCombie WR, Kostroff K, Spector DL. Bhatia S, et al. Among authors: arun g. Cancer Res. 2022 Apr 1;82(7):1174-1192. doi: 10.1158/0008-5472.CAN-21-2807. Cancer Res. 2022. PMID: 35180770 Free PMC article.

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