Haass C - Search Results

1

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M, Haass C. Parhizkar S, et al. Among authors: haass c. Nat Neurosci. 2019 Feb;22(2):191-204. doi: 10.1038/s41593-018-0296-9. Epub 2019 Jan 7. Nat Neurosci. 2019. PMID: 30617257 Free PMC article.

2

Amyloid beta-peptide is produced by cultured cells during normal metabolism.

Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, Lieberburg I, Koo EH, Schenk D, Teplow DB, et al. Haass C, et al. Nature. 1992 Sep 24;359(6393):322-5. doi: 10.1038/359322a0. Nature. 1992. PMID: 1383826

3

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production.

Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ. Citron M, et al. Among authors: haass c. Nature. 1992 Dec 17;360(6405):672-4. doi: 10.1038/360672a0. Nature. 1992. PMID: 1465129

4

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

Haass C, Koo EH, Mellon A, Hung AY, Selkoe DJ. Haass C, et al. Nature. 1992 Jun 11;357(6378):500-3. doi: 10.1038/357500a0. Nature. 1992. PMID: 1608449

5

Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion.

Haass C, Hung AY, Selkoe DJ. Haass C, et al. J Neurosci. 1991 Dec;11(12):3783-93. doi: 10.1523/JNEUROSCI.11-12-03783.1991. J Neurosci. 1991. PMID: 1744690 Free PMC article.

6

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.

Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ. Haass C, et al. Nat Med. 1995 Dec;1(12):1291-6. doi: 10.1038/nm1295-1291. Nat Med. 1995. PMID: 7489411

7

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C. Steiner H, et al. Among authors: haass c. Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. doi: 10.1007/s004060050098. Eur Arch Psychiatry Clin Neurosci. 1999. PMID: 10653281 Review.

8

The biological and pathological function of presenilin proteins--simple cell systems and a worm in Alzheimer's disease research.

Haass C, Baumeister R. Haass C, et al. Eur Arch Psychiatry Clin Neurosci. 1999;249 Suppl 3:23-7. doi: 10.1007/pl00014169. Eur Arch Psychiatry Clin Neurosci. 1999. PMID: 10654096 Review.

9

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch.

Capell A, Steiner H, Romig H, Keck S, Baader M, Grim MG, Baumeister R, Haass C. Capell A, et al. Among authors: haass c. Nat Cell Biol. 2000 Apr;2(4):205-11. doi: 10.1038/35008626. Nat Cell Biol. 2000. PMID: 10783238

10

Maturation and pro-peptide cleavage of beta-secretase.

Capell A, Steiner H, Willem M, Kaiser H, Meyer C, Walter J, Lammich S, Multhaup G, Haass C. Capell A, et al. Among authors: haass c. J Biol Chem. 2000 Oct 6;275(40):30849-54. doi: 10.1074/jbc.M003202200. J Biol Chem. 2000. PMID: 10801872 Free article.

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