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Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.
Sperandio D, Aktoudianakis V, Babaoglu K, Chen X, Elbel K, Chin G, Corkey B, Du J, Jiang B, Kobayashi T, Mackman R, Martinez R, Yang H, Zablocki J, Kusam S, Jordan K, Webb H, Bates JG, Lad L, Mish M, Niedziela-Majka A, Metobo S, Sapre A, Hung M, Jin D, Fung W, Kan E, Eisenberg G, Larson N, Newby ZER, Lansdon E, Tay C, Neve RM, Shevick SL, Breckenridge DG. Sperandio D, et al. Among authors: eisenberg g. Bioorg Med Chem. 2019 Feb 1;27(3):457-469. doi: 10.1016/j.bmc.2018.11.020. Epub 2018 Nov 15. Bioorg Med Chem. 2019. PMID: 30606676
A novel pulsed electromagnetic field device as an adjunct therapy to surgical treatment of distal radius fractures: a prospective, double-blind, sham-controlled, randomized pilot study.
Factor S, Druckmann I, Kazum E, Atlan F, Tordjman D, Rosenblatt Y, Eisenberg G, Pritsch T. Factor S, et al. Among authors: eisenberg g. Arch Orthop Trauma Surg. 2024 Jan;144(1):543-550. doi: 10.1007/s00402-023-05117-0. Epub 2023 Nov 16. Arch Orthop Trauma Surg. 2024. PMID: 37971511 Clinical Trial.
The future of affordable cancer immunotherapy.
Schaft N, Dörrie J, Schuler G, Schuler-Thurner B, Sallam H, Klein S, Eisenberg G, Frankenburg S, Lotem M, Khatib A. Schaft N, et al. Among authors: eisenberg g. Front Immunol. 2023 Sep 6;14:1248867. doi: 10.3389/fimmu.2023.1248867. eCollection 2023. Front Immunol. 2023. PMID: 37736099 Free PMC article. Review.
Conserved allosteric inhibition mechanism in SLC1 transporters.
Dong Y, Wang J, Garibsingh RA, Hutchinson K, Shi Y, Eisenberg G, Yu X, Schlessinger A, Grewer C. Dong Y, et al. Among authors: eisenberg g. Elife. 2023 Mar 1;12:e83464. doi: 10.7554/eLife.83464. Elife. 2023. PMID: 36856089 Free PMC article.
116 results