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Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol.
Guo Y, Zhao M, Bo T, Ma S, Yuan Z, Chen W, He Z, Hou X, Liu J, Zhang Z, Zhu Q, Wang Q, Lin X, Yang Z, Cui M, Liu L, Li Y, Yu C, Qi X, Wang Q, Zhang H, Guan Q, Zhao L, Xuan S, Yan H, Lin Y, Wang L, Li Q, Song Y, Gao L, Zhao J. Guo Y, et al. Among authors: he z. Cell Res. 2019 Feb;29(2):151-166. doi: 10.1038/s41422-018-0123-6. Epub 2018 Dec 17. Cell Res. 2019. PMID: 30559440 Free PMC article.
FSH signaling is involved in affective disorders.
Bi WK, Luan SS, Wang J, Wu SS, Jin XC, Fu YL, Gao L, Zhao JJ, He Z. Bi WK, et al. Among authors: he z. Biochem Biophys Res Commun. 2020 May 14;525(4):915-920. doi: 10.1016/j.bbrc.2020.03.039. Epub 2020 Mar 11. Biochem Biophys Res Commun. 2020. PMID: 32171529
FSHR ablation induces depression-like behaviors.
Bi WK, Shao SS, Li ZW, Ruan YW, Luan SS, Dong ZH, Wang J, Wu SS, Guo T, Ma SZ, Gao L, Zhao JJ, He Z. Bi WK, et al. Among authors: he z. Acta Pharmacol Sin. 2020 Aug;41(8):1033-1040. doi: 10.1038/s41401-020-0384-8. Epub 2020 Mar 18. Acta Pharmacol Sin. 2020. PMID: 32203083 Free PMC article.
Berberine improves intralipid-induced insulin resistance in murine.
Dong ZH, Lin HY, Chen FL, Che XQ, Bi WK, Shi SL, Wang J, Gao L, He Z, Zhao JJ. Dong ZH, et al. Among authors: he z. Acta Pharmacol Sin. 2021 May;42(5):735-743. doi: 10.1038/s41401-020-0493-4. Epub 2020 Aug 7. Acta Pharmacol Sin. 2021. PMID: 32770172 Free PMC article.
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