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Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol.
Guo Y, Zhao M, Bo T, Ma S, Yuan Z, Chen W, He Z, Hou X, Liu J, Zhang Z, Zhu Q, Wang Q, Lin X, Yang Z, Cui M, Liu L, Li Y, Yu C, Qi X, Wang Q, Zhang H, Guan Q, Zhao L, Xuan S, Yan H, Lin Y, Wang L, Li Q, Song Y, Gao L, Zhao J. Guo Y, et al. Among authors: chen w. Cell Res. 2019 Feb;29(2):151-166. doi: 10.1038/s41422-018-0123-6. Epub 2018 Dec 17. Cell Res. 2019. PMID: 30559440 Free PMC article.
A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2.
Li Y, Song Y, Zhao M, Guo Y, Yu C, Chen W, Shao S, Xu C, Zhou X, Zhao L, Zhang Z, Bo T, Xia Y, Proud CG, Wang X, Wang L, Zhao J, Gao L. Li Y, et al. Among authors: chen w. Hepatology. 2017 Aug;66(2):481-497. doi: 10.1002/hep.29206. Epub 2017 Jun 27. Hepatology. 2017. PMID: 28395113 Free PMC article.
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