Wen H - Search Results

1

O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity.

Li T, Li X, Attri KS, Liu C, Li L, Herring LE, Asara JM, Lei YL, Singh PK, Gao C, Wen H. Li T, et al. Among authors: wen h. Cell Host Microbe. 2018 Dec 12;24(6):791-803.e6. doi: 10.1016/j.chom.2018.11.001. Cell Host Microbe. 2018. PMID: 30543776 Free PMC article.

2

Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm.

Wen H, Lei Y, Eun SY, Ting JP. Wen H, et al. J Exp Med. 2010 Dec 20;207(13):2943-57. doi: 10.1084/jem.20101138. Epub 2010 Nov 22. J Exp Med. 2010. PMID: 21098092 Free PMC article.

3

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.

Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Wen H, et al. Nat Immunol. 2011 May;12(5):408-15. doi: 10.1038/ni.2022. Epub 2011 Apr 10. Nat Immunol. 2011. PMID: 21478880 Free PMC article.

4

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP. Lei Y, et al. Among authors: wen h, wen kw. Immunity. 2012 Jun 29;36(6):933-46. doi: 10.1016/j.immuni.2012.03.025. Immunity. 2012. PMID: 22749352 Free PMC article.

5

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy.

Lei Y, Wen H, Ting JP. Lei Y, et al. Among authors: wen h. Autophagy. 2013 Mar;9(3):432-3. doi: 10.4161/auto.23026. Epub 2013 Jan 15. Autophagy. 2013. PMID: 23321557 Free PMC article.

6

Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation.

Zhao C, Gillette DD, Li X, Zhang Z, Wen H. Zhao C, et al. Among authors: wen h. J Biol Chem. 2014 Jun 13;289(24):17020-9. doi: 10.1074/jbc.M114.563114. Epub 2014 May 5. J Biol Chem. 2014. PMID: 24798340 Free PMC article.

7

EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex.

Lei Y, Kansy BA, Li J, Cong L, Liu Y, Trivedi S, Wen H, Ting JP, Ouyang H, Ferris RL. Lei Y, et al. Among authors: wen h. Oncogene. 2016 Sep 8;35(36):4698-707. doi: 10.1038/onc.2016.11. Epub 2016 Feb 15. Oncogene. 2016. PMID: 26876213 Free PMC article.

8

NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.

Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. Guo H, et al. Among authors: wen h. Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001. Cell Host Microbe. 2016. PMID: 27078069 Free PMC article.

9

Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation.

Li X, Zhang Z, Li L, Gong W, Lazenby AJ, Swanson BJ, Herring LE, Asara JM, Singer JD, Wen H. Li X, et al. Among authors: wen h. J Exp Med. 2017 Apr 3;214(4):1093-1109. doi: 10.1084/jem.20161105. Epub 2017 Mar 9. J Exp Med. 2017. PMID: 28280036 Free PMC article.

10

NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.

Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H. Cheng L, et al. Among authors: wen h. J Neuroinflammation. 2018 Aug 29;15(1):243. doi: 10.1186/s12974-018-1289-z. J Neuroinflammation. 2018. PMID: 30157869 Free PMC article.

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