LaBelle JL - Search Results

1

Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP).

Ludwig LM, Maxcy KL, LaBelle JL. Ludwig LM, et al. Among authors: labelle jl. Methods Mol Biol. 2019;1877:77-91. doi: 10.1007/978-1-4939-8861-7_5. Methods Mol Biol. 2019. PMID: 30535999 Free PMC article.

2

Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.

Edwards AL, Gavathiotis E, LaBelle JL, Braun CR, Opoku-Nsiah KA, Bird GH, Walensky LD. Edwards AL, et al. Among authors: labelle jl. Chem Biol. 2013 Jul 25;20(7):888-902. doi: 10.1016/j.chembiol.2013.06.007. Chem Biol. 2013. PMID: 23890007 Free PMC article.

3

Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation.

Ludwig LM, Nassin ML, Hadji A, LaBelle JL. Ludwig LM, et al. Among authors: labelle jl. Front Pediatr. 2016 Dec 21;4:135. doi: 10.3389/fped.2016.00135. eCollection 2016. Front Pediatr. 2016. PMID: 28066751 Free PMC article. Review.

4

RNA Polymerase Tags To Monitor Multidimensional Protein-Protein Interactions Reveal Pharmacological Engagement of Bcl-2 Proteins.

Pu J, Dewey JA, Hadji A, LaBelle JL, Dickinson BC. Pu J, et al. Among authors: labelle jl. J Am Chem Soc. 2017 Aug 30;139(34):11964-11972. doi: 10.1021/jacs.7b06152. Epub 2017 Aug 15. J Am Chem Soc. 2017. PMID: 28767232 Free PMC article.

5

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization.

Ludwig LM, Roach LE, Katz SG, LaBelle JL. Ludwig LM, et al. Among authors: labelle jl. Apoptosis. 2020 Apr;25(3-4):247-260. doi: 10.1007/s10495-020-01593-6. Apoptosis. 2020. PMID: 31993851 Free PMC article.

6

Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells.

Ludwig LM, Hawley KM, Banks DB, Thomas-Toth AT, Blazar BR, McNerney ME, Leverson JD, LaBelle JL. Ludwig LM, et al. Among authors: labelle jl. Cell Death Dis. 2021 Oct 27;12(11):1005. doi: 10.1038/s41419-021-04285-4. Cell Death Dis. 2021. PMID: 34707089 Free PMC article.

7

Dissection of the BCL-2 family signaling network with stabilized alpha-helices of BCL-2 domains.

Pitter K, Bernal F, Labelle J, Walensky LD. Pitter K, et al. Methods Enzymol. 2008;446:387-408. doi: 10.1016/S0076-6879(08)01623-6. Methods Enzymol. 2008. PMID: 18603135 Free PMC article.

8

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.

LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.

9

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.

Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, Look AT, Walensky LD, Kelliher MA, Gutierrez A. Reynolds C, et al. Among authors: labelle jl. Leukemia. 2014 Sep;28(9):1819-27. doi: 10.1038/leu.2014.78. Epub 2014 Feb 20. Leukemia. 2014. PMID: 24552990 Free PMC article.

10

Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells.

Katz SG, Labelle JL, Meng H, Valeriano RP, Fisher JK, Sun H, Rodig SJ, Kleinstein SH, Walensky LD. Katz SG, et al. Among authors: labelle jl. Blood. 2014 Feb 6;123(6):884-93. doi: 10.1182/blood-2013-04-499079. Epub 2013 Dec 18. Blood. 2014. PMID: 24352880 Free PMC article.

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