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Page 1
Metabolite changes in blood predict the onset of tuberculosis.
Weiner J 3rd, Maertzdorf J, Sutherland JS, Duffy FJ, Thompson E, Suliman S, McEwen G, Thiel B, Parida SK, Zyla J, Hanekom WA, Mohney RP, Boom WH, Mayanja-Kizza H, Howe R, Dockrell HM, Ottenhoff THM, Scriba TJ, Zak DE, Walzl G, Kaufmann SHE; GC6-74 consortium. Weiner J 3rd, et al. Among authors: zak de. Nat Commun. 2018 Dec 6;9(1):5208. doi: 10.1038/s41467-018-07635-7. Nat Commun. 2018. PMID: 30523338 Free PMC article.
A blood RNA signature for tuberculosis disease risk: a prospective cohort study.
Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff THM, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SHE, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups. Zak DE, et al. Lancet. 2016 Jun 4;387(10035):2312-2322. doi: 10.1016/S0140-6736(15)01316-1. Epub 2016 Mar 24. Lancet. 2016. PMID: 27017310 Free PMC article.
Predicting tuberculosis risk - Authors' reply.
Zak D, Scriba TJ, Hatherill M, Penn-Nicholson A, Hanekom W. Zak D, et al. Lancet. 2016 Nov 5;388(10057):2233-2234. doi: 10.1016/S0140-6736(16)31653-1. Lancet. 2016. PMID: 27825498 No abstract available.
Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice.
Parihar SP, Ozturk M, Marakalala MJ, Loots DT, Hurdayal R, Maasdorp DB, Van Reenen M, Zak DE, Darboe F, Penn-Nicholson A, Hanekom WA, Leitges M, Scriba TJ, Guler R, Brombacher F. Parihar SP, et al. Among authors: zak de. Mucosal Immunol. 2018 Mar;11(2):496-511. doi: 10.1038/mi.2017.68. Epub 2017 Aug 9. Mucosal Immunol. 2018. PMID: 28832027 Free article.
Host blood RNA signatures predict the outcome of tuberculosis treatment.
Thompson EG, Du Y, Malherbe ST, Shankar S, Braun J, Valvo J, Ronacher K, Tromp G, Tabb DL, Alland D, Shenai S, Via LE, Warwick J, Aderem A, Scriba TJ, Winter J, Walzl G, Zak DE; Catalysis TB–Biomarker Consortium. Thompson EG, et al. Among authors: zak de. Tuberculosis (Edinb). 2017 Dec;107:48-58. doi: 10.1016/j.tube.2017.08.004. Epub 2017 Aug 12. Tuberculosis (Edinb). 2017. PMID: 29050771 Free PMC article.
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.
Scriba TJ, Penn-Nicholson A, Shankar S, Hraha T, Thompson EG, Sterling D, Nemes E, Darboe F, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Johnson JL, Boom WH, Hatherill M, Valvo J, De Groote MA, Ochsner UA, Aderem A, Hanekom WA, Zak DE; other members of the ACS cohort study team. Scriba TJ, et al. Among authors: de groote ma, zak de. PLoS Pathog. 2017 Nov 16;13(11):e1006687. doi: 10.1371/journal.ppat.1006687. eCollection 2017 Nov. PLoS Pathog. 2017. PMID: 29145483 Free PMC article. Clinical Trial.
Diagnostic performance of an optimized transcriptomic signature of risk of tuberculosis in cryopreserved peripheral blood mononuclear cells.
Darboe F, Mbandi SK, Thompson EG, Fisher M, Rodo M, van Rooyen M, Filander E, Bilek N, Mabwe S, Hatherill M, Zak DE, Penn-Nicholson A, Scriba TJ; SATVI Clinical Immunology Team. Darboe F, et al. Among authors: zak de. Tuberculosis (Edinb). 2018 Jan;108:124-126. doi: 10.1016/j.tube.2017.11.001. Epub 2017 Nov 6. Tuberculosis (Edinb). 2018. PMID: 29523312 No abstract available.
Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.
Suliman S, Thompson EG, Sutherland J, Weiner J 3rd, Ota MOC, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ, Hill PC, Hughes EJ, Stanley K, Downing K, Fisher ML, Valvo J, Parida SK, van der Spuy G, Tromp G, Adetifa IMO, Donkor S, Howe R, Mayanja-Kizza H, Boom WH, Dockrell HM, Ottenhoff THM, Hatherill M, Aderem A, Hanekom WA, Scriba TJ, Kaufmann SHE, Zak DE, Walzl G; GC6-74 cohort study team, The ACS cohort study team. Suliman S, et al. Among authors: zak de. Am J Respir Crit Care Med. 2018 May 1;197(9):1198-1208. doi: 10.1164/rccm.201711-2340OC. Am J Respir Crit Care Med. 2018. PMID: 29624071 Free PMC article.
52 results