Campagna J - Search Results

1

A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.

Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V. Campagna J, et al. Sci Rep. 2018 Dec 4;8(1):17574. doi: 10.1038/s41598-018-35687-8. Sci Rep. 2018. PMID: 30514854 Free PMC article.

2

AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease.

Descamps O, Spilman P, Zhang Q, Libeu CP, Poksay K, Gorostiza O, Campagna J, Jagodzinska B, Bredesen DE, John V. Descamps O, et al. Among authors: campagna j. J Alzheimers Dis. 2013;37(2):343-55. doi: 10.3233/JAD-130578. J Alzheimers Dis. 2013. PMID: 23948888 Free PMC article.

3

The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model.

Spilman P, Descamps O, Gorostiza O, Peters-Libeu C, Poksay KS, Matalis A, Campagna J, Patent A, Rao R, John V, Bredesen DE. Spilman P, et al. Among authors: campagna j. Brain Res. 2014 Mar 10;1551:25-44. doi: 10.1016/j.brainres.2013.12.029. Epub 2013 Dec 31. Brain Res. 2014. PMID: 24389031 Free PMC article.

4

sAβPPα is a Potent Endogenous Inhibitor of BACE1.

Peters-Libeu C, Campagna J, Mitsumori M, Poksay KS, Spilman P, Sabogal A, Bredesen DE, John V. Peters-Libeu C, et al. Among authors: campagna j. J Alzheimers Dis. 2015;47(3):545-55. doi: 10.3233/JAD-150282. J Alzheimers Dis. 2015. PMID: 26401691

5

Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.

Spilman PR, Corset V, Gorostiza O, Poksay KS, Galvan V, Zhang J, Rao R, Peters-Libeu C, Vincelette J, McGeehan A, Dvorak-Ewell M, Beyer J, Campagna J, Bankiewicz K, Mehlen P, John V, Bredesen DE. Spilman PR, et al. Among authors: campagna j. J Alzheimers Dis. 2016 Mar 8;52(1):223-42. doi: 10.3233/JAD-151046. J Alzheimers Dis. 2016. PMID: 27060954

6

C-O bond Formation in a Microfluidic Reactor: High Yield S_NAr Substitution of Heteroaryl Chlorides.

Alam MP, Jagodzinska B, Campagna J, Spilman P, John V. Alam MP, et al. Among authors: campagna j. Tetrahedron Lett. 2016 May 11;57(19):2059-2062. doi: 10.1016/j.tetlet.2016.03.095. Tetrahedron Lett. 2016. PMID: 27152054 Free PMC article.

7

Nanoscale Extracellular Vesicle Analysis in Alzheimer's Disease Diagnosis and Therapy.

Heinzelman P, Bilousova T, Campagna J, John V. Heinzelman P, et al. Among authors: campagna j. Int J Alzheimers Dis. 2016;2016:8053139. doi: 10.1155/2016/8053139. Epub 2016 Apr 26. Int J Alzheimers Dis. 2016. PMID: 27213078 Free PMC article. Review.

8

Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production.

Poksay KS, Sheffler DJ, Spilman P, Campagna J, Jagodzinska B, Descamps O, Gorostiza O, Matalis A, Mullenix M, Bredesen DE, Cosford ND, John V. Poksay KS, et al. Among authors: campagna j. Front Pharmacol. 2017 Feb 15;8:46. doi: 10.3389/fphar.2017.00046. eCollection 2017. Front Pharmacol. 2017. PMID: 28261092 Free PMC article.

9

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery.

Subbiah N, Campagna J, Spilman P, Alam MP, Sharma S, Hokugo A, Nishimura I, John V. Subbiah N, et al. Among authors: campagna j. J Drug Deliv. 2017;2017:4759839. doi: 10.1155/2017/4759839. Epub 2017 Apr 5. J Drug Deliv. 2017. PMID: 28480080 Free PMC article.

10

Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.

Bilousova T, Elias C, Miyoshi E, Alam MP, Zhu C, Campagna J, Vadivel K, Jagodzinska B, Gylys KH, John V. Bilousova T, et al. Among authors: campagna j. Biochem Biophys Res Commun. 2018 May 23;499(4):751-757. doi: 10.1016/j.bbrc.2018.03.209. Epub 2018 Apr 9. Biochem Biophys Res Commun. 2018. PMID: 29604274 Free PMC article.

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