Siegmund K - Search Results

1

Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance.

Ryser MD, Yu M, Grady W, Siegmund K, Shibata D. Ryser MD, et al. Among authors: siegmund k. Sci Rep. 2018 Nov 23;8(1):17292. doi: 10.1038/s41598-018-35621-y. Sci Rep. 2018. PMID: 30470817 Free PMC article.

2

Diet, cancer and aging in DNA mismatch repair deficient mice.

Tsao JL, Dudley S, Kwok B, Nickel AE, Laird PW, Siegmund KD, Liskay RM, Shibata D. Tsao JL, et al. Carcinogenesis. 2002 Nov;23(11):1807-10. doi: 10.1093/carcin/23.11.1807. Carcinogenesis. 2002. PMID: 12419828

3

Age-related human small intestine methylation: evidence for stem cell niches.

Kim JY, Siegmund KD, Tavaré S, Shibata D. Kim JY, et al. BMC Med. 2005 Jun 23;3:10. doi: 10.1186/1741-7015-3-10. BMC Med. 2005. PMID: 15975143 Free PMC article.

4

Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.

Chu MW, Siegmund KD, Eckstam CL, Kim JY, Yang AS, Kanel GC, Tavaré S, Shibata D. Chu MW, et al. BMC Med Genet. 2007 Jul 31;8:50. doi: 10.1186/1471-2350-8-50. BMC Med Genet. 2007. PMID: 17672908 Free PMC article.

5

Inferring relative numbers of human leucocyte genome replications.

Chu M, Siegmund KD, Hao QL, Crooks GM, Tavaré S, Shibata D. Chu M, et al. Br J Haematol. 2008 Jun;141(6):862-71. doi: 10.1111/j.1365-2141.2008.07142.x. Epub 2008 Apr 10. Br J Haematol. 2008. PMID: 18410448 Free article.

6

Modeling DNA methylation in a population of cancer cells.

Siegmund KD, Marjoram P, Shibata D. Siegmund KD, et al. Stat Appl Genet Mol Biol. 2008;7(1):Article 18. doi: 10.2202/1544-6115.1374. Epub 2008 Jun 22. Stat Appl Genet Mol Biol. 2008. PMID: 18597664

7

Older individuals appear to acquire mitotically older colorectal cancers.

Woo YJ, Siegmund KD, Tavaré S, Shibata D. Woo YJ, et al. J Pathol. 2009 Mar;217(4):483-8. doi: 10.1002/path.2506. J Pathol. 2009. PMID: 19165870 Free PMC article.

8

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.

Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D. Siegmund KD, et al. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4828-33. doi: 10.1073/pnas.0810276106. Epub 2009 Mar 4. Proc Natl Acad Sci U S A. 2009. PMID: 19261858 Free PMC article.

9

Many colorectal cancers are "flat" clonal expansions.

Siegmund KD, Marjoram P, Tavaré S, Shibata D. Siegmund KD, et al. Cell Cycle. 2009 Jul 15;8(14):2187-93. doi: 10.4161/cc.8.14.9151. Epub 2009 Jul 1. Cell Cycle. 2009. PMID: 19556889 Free PMC article. Review.

10

Hormone therapy, DNA methylation and colon cancer.

Wu AH, Siegmund KD, Long TI, Cozen W, Wan P, Tseng CC, Shibata D, Laird PW. Wu AH, et al. Carcinogenesis. 2010 Jun;31(6):1060-7. doi: 10.1093/carcin/bgq009. Epub 2010 Jan 11. Carcinogenesis. 2010. PMID: 20064828 Free PMC article.

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