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Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex.
Pollen AA, Nowakowski TJ, Shuga J, Wang X, Leyrat AA, Lui JH, Li N, Szpankowski L, Fowler B, Chen P, Ramalingam N, Sun G, Thu M, Norris M, Lebofsky R, Toppani D, Kemp DW 2nd, Wong M, Clerkson B, Jones BN, Wu S, Knutsson L, Alvarado B, Wang J, Weaver LS, May AP, Jones RC, Unger MA, Kriegstein AR, West JA. Pollen AA, et al. Among authors: alvarado b. Nat Biotechnol. 2014 Oct;32(10):1053-8. doi: 10.1038/nbt.2967. Epub 2014 Aug 3. Nat Biotechnol. 2014. PMID: 25086649 Free PMC article.
Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex.
Nowakowski TJ, Bhaduri A, Pollen AA, Alvarado B, Mostajo-Radji MA, Di Lullo E, Haeussler M, Sandoval-Espinosa C, Liu SJ, Velmeshev D, Ounadjela JR, Shuga J, Wang X, Lim DA, West JA, Leyrat AA, Kent WJ, Kriegstein AR. Nowakowski TJ, et al. Among authors: alvarado b. Science. 2017 Dec 8;358(6368):1318-1323. doi: 10.1126/science.aap8809. Science. 2017. PMID: 29217575 Free PMC article.
Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment.
Müller S, Kohanbash G, Liu SJ, Alvarado B, Carrera D, Bhaduri A, Watchmaker PB, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim DA, Aghi M, Okada H, Diaz A. Müller S, et al. Among authors: alvarado b. Genome Biol. 2017 Dec 20;18(1):234. doi: 10.1186/s13059-017-1362-4. Genome Biol. 2017. PMID: 29262845 Free PMC article.
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution.
Pollen AA, Bhaduri A, Andrews MG, Nowakowski TJ, Meyerson OS, Mostajo-Radji MA, Di Lullo E, Alvarado B, Bedolli M, Dougherty ML, Fiddes IT, Kronenberg ZN, Shuga J, Leyrat AA, West JA, Bershteyn M, Lowe CB, Pavlovic BJ, Salama SR, Haussler D, Eichler EE, Kriegstein AR. Pollen AA, et al. Among authors: alvarado b. Cell. 2019 Feb 7;176(4):743-756.e17. doi: 10.1016/j.cell.2019.01.017. Cell. 2019. PMID: 30735633 Free PMC article.
Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.
Mayer S, Chen J, Velmeshev D, Mayer A, Eze UC, Bhaduri A, Cunha CE, Jung D, Arjun A, Li E, Alvarado B, Wang S, Lovegren N, Gonzales ML, Szpankowski L, Leyrat A, West JAA, Panagiotakos G, Alvarez-Buylla A, Paredes MF, Nowakowski TJ, Pollen AA, Kriegstein AR. Mayer S, et al. Among authors: alvarado b. Neuron. 2019 Apr 3;102(1):143-158.e7. doi: 10.1016/j.neuron.2019.01.027. Epub 2019 Feb 12. Neuron. 2019. PMID: 30770253 Free PMC article.
The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation.
Wang L, Babikir H, Müller S, Yagnik G, Shamardani K, Catalan F, Kohanbash G, Alvarado B, Di Lullo E, Kriegstein A, Shah S, Wadhwa H, Chang SM, Phillips JJ, Aghi MK, Diaz AA. Wang L, et al. Among authors: alvarado b. Cancer Discov. 2019 Dec;9(12):1708-1719. doi: 10.1158/2159-8290.CD-19-0329. Epub 2019 Sep 25. Cancer Discov. 2019. PMID: 31554641 Free PMC article.
Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR. Bhaduri A, et al. Among authors: alvarado b. Cell Stem Cell. 2020 Jan 2;26(1):48-63.e6. doi: 10.1016/j.stem.2019.11.015. Cell Stem Cell. 2020. PMID: 31901251 Free PMC article.
Direct analysis of brain phenotypes via neural blastocyst complementation.
Dai HQ, Liang Z, Chang AN, Chapdelaine-Williams AM, Alvarado B, Pollen AA, Alt FW, Schwer B. Dai HQ, et al. Among authors: alvarado b. Nat Protoc. 2020 Oct;15(10):3154-3181. doi: 10.1038/s41596-020-0364-y. Epub 2020 Aug 10. Nat Protoc. 2020. PMID: 32778838 Free PMC article.
Machine learning dissection of human accelerated regions in primate neurodevelopment.
Whalen S, Inoue F, Ryu H, Fair T, Markenscoff-Papadimitriou E, Keough K, Kircher M, Martin B, Alvarado B, Elor O, Laboy Cintron D, Williams A, Hassan Samee MA, Thomas S, Krencik R, Ullian EM, Kriegstein A, Rubenstein JL, Shendure J, Pollen AA, Ahituv N, Pollard KS. Whalen S, et al. Among authors: alvarado b. Neuron. 2023 Mar 15;111(6):857-873.e8. doi: 10.1016/j.neuron.2022.12.026. Epub 2023 Jan 13. Neuron. 2023. PMID: 36640767 Free PMC article.
99 results