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Inflammation and Hypoxia: HIF and PHD Isoform Selectivity.
Watts ER, Walmsley SR. Watts ER, et al. Among authors: walmsley sr. Trends Mol Med. 2019 Jan;25(1):33-46. doi: 10.1016/j.molmed.2018.10.006. Epub 2018 Nov 12. Trends Mol Med. 2019. PMID: 30442494 Free article. Review.
The role of HIF-1alpha in myeloid cell inflammation.
Walmsley SR, Cadwallader KA, Chilvers ER. Walmsley SR, et al. Trends Immunol. 2005 Aug;26(8):434-9. doi: 10.1016/j.it.2005.06.007. Trends Immunol. 2005. PMID: 15979406 Review.
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, Ratcliffe PJ, Maxwell PH, Carmeliet P, Whyte MK. Walmsley SR, et al. J Clin Invest. 2011 Mar;121(3):1053-63. doi: 10.1172/JCI43273. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317538 Free PMC article.
Hypoxia and host pathogen responses.
Walmsley SR, Rupp J. Walmsley SR, et al. Microbes Infect. 2017 Mar;19(3):143. doi: 10.1016/j.micinf.2017.01.006. Epub 2017 Jan 20. Microbes Infect. 2017. PMID: 28115212 Free article. No abstract available.
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.
Sadiku P, Willson JA, Dickinson RS, Murphy F, Harris AJ, Lewis A, Sammut D, Mirchandani AS, Ryan E, Watts ER, Thompson AAR, Marriott HM, Dockrell DH, Taylor CT, Schneider M, Maxwell PH, Chilvers ER, Mazzone M, Moral V, Pugh CW, Ratcliffe PJ, Schofield CJ, Ghesquiere B, Carmeliet P, Whyte MK, Walmsley SR. Sadiku P, et al. Among authors: walmsley sr. J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14. J Clin Invest. 2017. PMID: 28805660 Free PMC article.
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo.
Harris AJ, Mirchandani AS, Lynch RW, Murphy F, Delaney L, Small D, Coelho P, Watts ER, Sadiku P, Griffith D, Dickinson RS, Clark E, Willson JA, Morrison T, Mazzone M, Carmeliet P, Ghesquiere B, O'Kane C, McAuley D, Jenkins SJ, Whyte MKB, Walmsley SR. Harris AJ, et al. Among authors: walmsley sr. Am J Respir Crit Care Med. 2019 Jul 15;200(2):235-246. doi: 10.1164/rccm.201808-1599OC. Am J Respir Crit Care Med. 2019. PMID: 30849228 Free PMC article.
67 results