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Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents.
Zhang Y, Zhao Y, Tebben AJ, Sheriff S, Ruzanov M, Fereshteh MP, Fan Y, Lippy J, Swanson J, Ho CP, Wautlet BS, Rose A, Parrish K, Yang Z, Donnell AF, Zhang L, Fink BE, Vite GD, Augustine-Rauch K, Fargnoli J, Borzilleri RM. Zhang Y, et al. Among authors: ho cp. ACS Med Chem Lett. 2018 Oct 17;9(11):1117-1122. doi: 10.1021/acsmedchemlett.8b00357. eCollection 2018 Nov 8. ACS Med Chem Lett. 2018. PMID: 30429955 Free PMC article.
Heterobicyclic inhibitors of transforming growth factor beta receptor I (TGFβRI).
Harikrishnan LS, Warrier J, Tebben AJ, Tonukunuru G, Madduri SR, Baligar V, Mannoori R, Seshadri B, Rahaman H, Arunachalam PN, Dikundwar AG, Fink BE, Fargnoli J, Fereshteh M, Fan Y, Lippy J, Ho CP, Wautlet B, Sheriff S, Ruzanov M, Borzilleri RM. Harikrishnan LS, et al. Among authors: ho cp. Bioorg Med Chem. 2018 Mar 1;26(5):1026-1034. doi: 10.1016/j.bmc.2018.01.014. Epub 2018 Jan 31. Bioorg Med Chem. 2018. PMID: 29422332
Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance.
Liu J, Curtin J, You D, Hillerman S, Li-Wang B, Eraslan R, Xie J, Swanson J, Ho CP, Oppenheimer S, Warrack BM, McNaney CA, Nelson DM, Blum J, Kim T, Fereshteh M, Reily M, Shipkova P, Murtaza A, Sanjuan M, Hunt JT, Salter-Cid L. Liu J, et al. Among authors: ho cp. PLoS One. 2019 Mar 26;14(3):e0212670. doi: 10.1371/journal.pone.0212670. eCollection 2019. PLoS One. 2019. PMID: 30913212 Free PMC article.
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor.
Carboni JM, Lee AV, Hadsell DL, Rowley BR, Lee FY, Bol DK, Camuso AE, Gottardis M, Greer AF, Ho CP, Hurlburt W, Li A, Saulnier M, Velaparthi U, Wang C, Wen ML, Westhouse RA, Wittman M, Zimmermann K, Rupnow BA, Wong TW. Carboni JM, et al. Among authors: ho cp. Cancer Res. 2005 May 1;65(9):3781-7. doi: 10.1158/0008-5472.CAN-04-4602. Cancer Res. 2005. PMID: 15867374
169 results