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Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes.
Jiao Y, Davis JE, Rautela J, Carrington EM, Ludford-Menting MJ, Goh W, Delconte RB, Souza-Fonseca-Guimaraes F, Koldej R, Gray D, Huang D, Kile BT, Lew AM, Ritchie DS, Huntington ND. Jiao Y, et al. Among authors: gray d. Cell Death Differ. 2019 Aug;26(8):1516-1530. doi: 10.1038/s41418-018-0228-y. Epub 2018 Nov 12. Cell Death Differ. 2019. PMID: 30420758 Free PMC article.
XIAP discriminates between type I and type II FAS-induced apoptosis.
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. Jost PJ, et al. Among authors: gray d. Nature. 2009 Aug 20;460(7258):1035-9. doi: 10.1038/nature08229. Epub 2009 Jul 22. Nature. 2009. PMID: 19626005 Free PMC article.
Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.
Mason KD, Lin A, Robb L, Josefsson EC, Henley KJ, Gray DH, Kile BT, Roberts AW, Strasser A, Huang DC, Waring P, O'Reilly LA. Mason KD, et al. Among authors: gray dh. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2599-604. doi: 10.1073/pnas.1215097110. Epub 2013 Jan 24. Proc Natl Acad Sci U S A. 2013. PMID: 23349374 Free PMC article.
CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NP, Linossi EM, Burns CJ, Carotta S, Gray DH, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND. Delconte RB, et al. Among authors: gray dh. Nat Immunol. 2016 Jul;17(7):816-24. doi: 10.1038/ni.3470. Epub 2016 May 23. Nat Immunol. 2016. PMID: 27213690
Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.
Le Texier L, Lineburg KE, Cao B, McDonald-Hyman C, Leveque-El Mouttie L, Nicholls J, Melino M, Nalkurthi BC, Alexander KA, Teal B, Blake SJ, Souza-Fonseca-Guimaraes F, Engwerda CR, Kuns RD, Lane SW, Teng M, Teh C, Gray D, Clouston AD, Nilsson SK, Blazar BR, Hill GR, MacDonald KP. Le Texier L, et al. Among authors: gray d. JCI Insight. 2016 Sep 22;1(15):e86850. doi: 10.1172/jci.insight.86850. JCI Insight. 2016. PMID: 27699243 Free PMC article.
Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival.
Viant C, Guia S, Hennessy RJ, Rautela J, Pham K, Bernat C, Goh W, Jiao Y, Delconte R, Roger M, Simon V, Souza-Fonseca-Guimaraes F, Grabow S, Belz GT, Kile BT, Strasser A, Gray D, Hodgkin PD, Beutler B, Vivier E, Ugolini S, Huntington ND. Viant C, et al. Among authors: gray d. J Exp Med. 2017 Feb;214(2):491-510. doi: 10.1084/jem.20160869. Epub 2017 Jan 5. J Exp Med. 2017. PMID: 28057804 Free PMC article.
2,800 results