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A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice.
Boudreau MW, Duraki D, Wang L, Mao C, Kim JE, Henn MA, Tang B, Fanning SW, Kiefer J, Tarasow TM, Bruckheimer EM, Moreno R, Mousses S, Greene GL, Roy EJ, Park BH, Fan TM, Nelson ER, Hergenrother PJ, Shapiro DJ. Boudreau MW, et al. Among authors: duraki d. Sci Transl Med. 2021 Jul 21;13(603):eabf1383. doi: 10.1126/scitranslmed.abf1383. Sci Transl Med. 2021. PMID: 34290053 Free PMC article.
Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-Induced Necrosis.
Ghosh S, Yang R, Duraki D, Zhu J, Kim JE, Jabeen M, Mao C, Dai X, Livezey MR, Boudreau MW, Park BH, Nelson ER, Hergenrother PJ, Shapiro DJ. Ghosh S, et al. Among authors: duraki d. Cancer Res. 2023 Sep 15;83(18):3115-3130. doi: 10.1158/0008-5472.CAN-23-0157. Cancer Res. 2023. PMID: 37522838 Free PMC article.