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Mutant enzymes challenge all assumptions.
Nottingham RM, Pfeffer SR. Nottingham RM, et al. Among authors: pfeffer sr. Elife. 2014 Feb 11;3:e02171. doi: 10.7554/eLife.02171. Elife. 2014. PMID: 24520166 Free PMC article.
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR. Purlyte E, et al. Among authors: pfeffer sr. EMBO J. 2018 Jan 4;37(1):1-18. doi: 10.15252/embj.201798099. Epub 2017 Dec 6. EMBO J. 2018. PMID: 29212815 Free PMC article.
LRRK2 and Rab GTPases.
Pfeffer SR. Pfeffer SR. Biochem Soc Trans. 2018 Dec 17;46(6):1707-1712. doi: 10.1042/BST20180470. Epub 2018 Nov 22. Biochem Soc Trans. 2018. PMID: 30467121 Review.
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR. Purlyte E, et al. Among authors: pfeffer sr. EMBO J. 2019 Jan 15;38(2):e101237. doi: 10.15252/embj.2018101237. EMBO J. 2019. PMID: 30647193 Free PMC article.
191 results