Sprenger HG - Search Results

1

Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.

Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T. Sprenger HG, et al. EMBO Mol Med. 2019 Jan;11(1):e9288. doi: 10.15252/emmm.201809288. EMBO Mol Med. 2019. PMID: 30389680 Free PMC article.

2

The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.

Wai T, Saita S, Nolte H, Müller S, König T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Mühlmeister M, Brandt U, Krüger M, Langer T. Wai T, et al. Among authors: sprenger hg. EMBO Rep. 2016 Dec;17(12):1844-1856. doi: 10.15252/embr.201642698. Epub 2016 Oct 13. EMBO Rep. 2016. PMID: 27737933 Free PMC article.

3

m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration.

Patron M, Sprenger HG, Langer T. Patron M, et al. Among authors: sprenger hg. Cell Res. 2018 Mar;28(3):296-306. doi: 10.1038/cr.2018.17. Epub 2018 Feb 16. Cell Res. 2018. PMID: 29451229 Free PMC article. Review.

4

Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.

Korwitz A, Merkwirth C, Richter-Dennerlein R, Tröder SE, Sprenger HG, Quirós PM, López-Otín C, Rugarli EI, Langer T. Korwitz A, et al. Among authors: sprenger hg. J Cell Biol. 2016 Jan 18;212(2):157-66. doi: 10.1083/jcb.201507022. J Cell Biol. 2016. PMID: 26783299 Free PMC article.

5

The Good and the Bad of Mitochondrial Breakups.

Sprenger HG, Langer T. Sprenger HG, et al. Trends Cell Biol. 2019 Nov;29(11):888-900. doi: 10.1016/j.tcb.2019.08.003. Epub 2019 Sep 5. Trends Cell Biol. 2019. PMID: 31495461 Review.

6

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.

MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T. MacVicar T, et al. Among authors: sprenger hg. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6. Nature. 2019. PMID: 31695197

7

Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.

Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M. Wani GA, et al. Among authors: sprenger hg. Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. Cell Rep. 2022. PMID: 35172139 Free article.

8

Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.

Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. Sprenger HG, et al. Nat Metab. 2021 May;3(5):636-650. doi: 10.1038/s42255-021-00385-9. Epub 2021 Apr 26. Nat Metab. 2021. PMID: 33903774 Free PMC article.

9

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.

Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC. Hammerschmidt P, et al. Among authors: sprenger hg. Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008. Cell. 2019. PMID: 31150623 Free article.

10

Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.

Brandt C, Nolte H, Henschke S, Engström Ruud L, Awazawa M, Morgan DA, Gabel P, Sprenger HG, Hess ME, Günther S, Langer T, Rahmouni K, Fenselau H, Krüger M, Brüning JC. Brandt C, et al. Among authors: sprenger hg. Cell. 2018 Nov 15;175(5):1321-1335.e20. doi: 10.1016/j.cell.2018.10.015. Cell. 2018. PMID: 30445039 Free PMC article.

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